Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.42 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7612390 | 1.00 | LMNA (0.54) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL10529810 | 1.00 | LMNA (0.54) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL4414640 | 1.00 | LMNA (0.54) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL5831487 | 1.00 | LMNA (0.54) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL24219844 | 1.00 | LMNA (0.54) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL3991828 | 1.00 | LMNA (0.54) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL23630665 | 1.00 | LMNA (0.54) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL7030936 | 1.00 | LMNA (0.54) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL7747262 | 1.00 | LMNA (0.54) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL11727258 | 1.00 | LMNA (0.54) | LMNAMAPTMAPK1CYP2D6SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4544512-A | ANTITUMOR AGENTS, FUNGICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-10-01 | — | — | US | disclosed |
| EP-0050460-B1 | TRIDECYLOXY- OR TETRADECYLOXY-PROPANE DERIVATIVES, AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 1985-07-10 | — | — | EP | disclosed |
| US-4426525-A | ANTITUMOR, ANTIMYCOTIC, ANTIPROTOZOA | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-01-17 | — | — | US | disclosed |
| EP-0050460-A2 | Tridecyloxy- or tetradecyloxy-propane derivatives, and their use | Takeda Chemical Industries, Ltd. (JP) | 1982-04-28 | — | — | EP | disclosed |