Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.61 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.61 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CDC25A | P30304 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 8/20 | 0.45 |
| ▸ | CA2 | P00918 | 8/20 | 0.45 |
| ▸ | CA9 | Q16790 | 7/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | CA3 | P07451 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10933039 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL10934826 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL3399123 | 0.98 | LPAR3 (0.58) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL11720155 | 0.90 | — | — | |
| SCHEMBL10934225 | 0.88 | LPAR3 (0.64) | LPAR3LPAR2LPAR1CYP3A4 | |
| SCHEMBL10934233 | 0.88 | LPAR3 (0.64) | LPAR3LPAR2LPAR1CYP3A4 | |
| SCHEMBL9463219 | 0.86 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL17686773 | 0.86 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL29085821 | 0.86 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL28954648 | 0.86 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4517002-A | Phosphorodiamide urease inhibitors and urease inhibited urea based fertilizer compositions | ALLIED CORPORATION (US) | 1985-05-14 | — | — | US | disclosed |
| EP-0119494-A1 | Urease inhibited urea based fertilizer compositions containing phosphorus compounds | ALLIED CORPORATION (US) | 1984-09-26 | — | — | EP | disclosed |