Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.58 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.58 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 7/20 | 0.43 |
| ▸ | CA2 | P00918 | 7/20 | 0.43 |
| ▸ | CA9 | Q16790 | 7/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA3 | P07451 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10934826 | 0.98 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL10935523 | 0.98 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL10933039 | 0.98 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL11720155 | 0.92 | — | — | |
| SCHEMBL10934233 | 0.86 | LPAR3 (0.64) | LPAR3LPAR2LPAR1CYP3A4 | |
| SCHEMBL10934225 | 0.86 | LPAR3 (0.64) | LPAR3LPAR2LPAR1CYP3A4 | |
| SCHEMBL1194563 | 0.85 | LPAR3 (0.58) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL9463219 | 0.83 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL21764574 | 0.83 | CYP3A4 (0.58) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL17686773 | 0.83 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144516-A1 | PREPARATION AND USE OF MAGNESIUM AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2010-06-10 | — | — | US | disclosed |
| EP-2142556-A1 | PREPARATION AND USE OF MAGNESIUM AMIDES | Ludwig-Maximilians-Universität München (DE) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008087057-A1 | PREPARATION AND USE OF MAGNESIUM AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) | 2008-07-24 | — | — | WO | disclosed |
| US-4517004-A | Aryl phosphoric triamide and aryl phosphorodiamidate urease and nitrification inhibitors and urease and nitrification inhibited urea and reduced nitrogen based fertilizer compositions | ALLIED CORPORATION (US) | 1985-05-14 | — | — | US | disclosed |
| US-4517004-A | Aryl phosphoric triamide and aryl phosphorodiamidate urease and nitrification inhibitors and urease and nitrification inhibited urea and reduced nitrogen based fertilizer compositions | ALLIED CORPORATION (US) | 1985-05-14 | — | — | US | disclosed |