Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.45 |
| ▸ | F10 | P00742 | 7/20 | 0.45 |
| ▸ | F7 | P08709 | 2/20 | 0.45 |
| ▸ | PLAU | P00749 | 11/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.43 |
| ▸ | PLG | P00747 | 7/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.43 |
| ▸ | PLAT | P00750 | 5/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10937015 | 0.85 | PLAU (0.46) | F2F10F7PLAUPRSS1 | |
| SCHEMBL10938176 | 0.84 | PLAU (0.48) | F2F10F7PLAUPRSS1 | |
| SCHEMBL10936558 | 0.82 | PLAU (0.44) | F2F10PLAUPRSS1PLG | |
| SCHEMBL7339710 | 0.81 | PLAU (0.60) | F2F10F7PLAUPRSS1 | |
| SCHEMBL10936183 | 0.81 | PLAU (0.43) | F2F10PLAUPRSS1PLG | |
| SCHEMBL10939658 | 0.81 | PLAU (0.43) | F2F10PLAUPRSS1PLG | |
| SCHEMBL10936655 | 0.81 | PLAU (0.43) | F2F10PLAUPRSS1PLG | |
| SCHEMBL10935100 | 0.81 | PLAU (0.43) | F2F10PLAUPRSS1PLG | |
| SCHEMBL7342686 | 0.80 | PLAU (0.48) | F2F10F7PLAUPRSS1 | |
| SCHEMBL7338914 | 0.80 | PLAU (0.50) | F2F10PLAUPRSS1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496584-A | ANTITRYPSIN, ANTIKALLIKREIN, ANTITHROMBIN OR ANTIPLASMIN AGENT | TORII & CO. LTD. (JP) | 1985-01-29 | — | — | US | disclosed |