Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 9/20 | 0.72 |
| ▸ | NPC1 | O15118 | 7/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.72 |
| ▸ | TP53 | P04637 | 2/20 | 0.72 |
| ▸ | ACP1 | P24666 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | MITF | O75030 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | APEX1 | P27695 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | STAT1 | P42224 | 1/20 | 0.65 |
| ▸ | CLK1 | P49759 | 1/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19844517 | 0.89 | RAB9A (0.72) | DYRK1ARAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL10935986 | 0.89 | DYRK1A (0.74) | DYRK1ARAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL14189669 | 0.87 | RAB9A (0.74) | DYRK1ARAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL29500269 | 0.86 | RAB9A (0.72) | DYRK1ARAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL29477216 | 0.86 | RAB9A (0.72) | DYRK1ARAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL28384921 | 0.86 | RAB9A (0.72) | DYRK1ARAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL7924717 | 0.86 | RAB9A (0.72) | DYRK1ARAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL11920138 | 0.86 | RAB9A (0.72) | DYRK1ARAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL2175580 | 0.85 | DYRK1A (1.00) | DYRK1ARAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL10936004 | 0.85 | DYRK1A (0.75) | DYRK1ARAB9ANPC1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051560-B1 | MONOAZOPIGMENTS CONTAINING HETEROCYCLIC NUCLEI, THEIR PREPARATION AND USE | CIBA-GEIGY AG (CH) | 1985-01-16 | — | — | EP | disclosed |
| US-4400319-A | Monoazo pigments containing heterocycles, and high-molecular organic materials dyed therewith | CIBA-GEIGY CORPORATION (US) | 1983-08-23 | — | — | US | disclosed |
| EP-0051560-A1 | Monoazopigments containing heterocyclic nuclei, their preparation and use | CIBA-GEIGY AG (CH) | 1982-05-12 | — | — | EP | disclosed |