Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MGAT2 | Q10469 | 2/20 | 0.38 |
| ▸ | RARB | P10826 | 4/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10933040 | 0.94 | KDM4E (0.51) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL10930409 | 0.94 | KDM4E (0.51) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL10929260 | 0.94 | KDM4E (0.51) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL10929232 | 0.93 | KDM4E (0.49) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL10930112 | 0.91 | KDM4E (0.45) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL10945415 | 0.89 | KDM4E (0.43) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL10897386 | 0.89 | KDM4E (0.56) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL10891965 | 0.89 | KDM4E (0.56) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL10891436 | 0.87 | KDM4E (0.54) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL10929944 | 0.86 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090183-B1 | POLYHALOGENATED AROMATIC COMPOUNDS | MERCK PATENT GmbH (DE) | 1986-02-19 | — | — | EP | disclosed |