Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.40 |
| ▸ | MEN1 | O00255 | 9/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ARNT | P27540 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10939130 | 1.00 | MAPT (0.40) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL10996988 | 0.88 | KMT2A (0.40) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL10996992 | 0.88 | KMT2A (0.40) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL11045441 | 0.80 | KMT2A (0.39) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL11045438 | 0.80 | KMT2A (0.39) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL7271751 | 0.77 | KDM4E (0.38) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL6232523 | 0.77 | KDM4E (0.38) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL6232530 | 0.77 | KDM4E (0.38) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL4800575 | 0.74 | MAPT (0.41) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL10729247 | 0.74 | MAPT (0.41) | MAPTALDH1A1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1985001940-A1 | DERIVATIVES OF 1,4-DIHYDROPYRIDINE, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANDOZ AG (CH) | 1985-05-09 | — | — | WO | disclosed |