Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232530 | 1.00 | KDM4E (0.38) | KDM4ECYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7271751 | 1.00 | KDM4E (0.38) | KDM4ECYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10729247 | 0.85 | MAPT (0.41) | KDM4ECYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4800575 | 0.85 | MAPT (0.41) | KDM4ECYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4800564 | 0.85 | MAPT (0.41) | KDM4ECYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11045441 | 0.84 | KMT2A (0.39) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL11045438 | 0.84 | KMT2A (0.39) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL11125601 | 0.82 | KMT2A (0.42) | KDM4ECYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10629783 | 0.79 | ALDH1A1 (0.36) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL10936766 | 0.77 | MAPT (0.40) | KDM4EALDH1A1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005437-A1 | AN IMPROVED PROCESS FOR THE MANUFACTURE OF ISRADIPINE. | SHASUN CHEMICALS AND DRUGS LIMITED (IN) | 2005-01-20 | — | — | WO | claimed |
| WO-2005005437-A1 | AN IMPROVED PROCESS FOR THE MANUFACTURE OF ISRADIPINE. | SHASUN CHEMICALS AND DRUGS LIMITED (IN) | 2005-01-20 | — | — | WO | disclosed |