Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | SAT1 | P21673 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | F13A1 | P00488 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974114 | 1.00 | SIGMAR1 (0.48) | SIGMAR1SAT1HDAC3HDAC4HDAC1 | |
| SCHEMBL6977232 | 0.98 | SAT1 (0.47) | SIGMAR1SAT1HDAC3HDAC4HDAC1 | |
| SCHEMBL19473289 | 0.96 | SAT1 (0.52) | SIGMAR1SAT1HDAC3HDAC4HDAC1 | |
| SCHEMBL6970039 | 0.94 | SIGMAR1 (0.52) | SIGMAR1SAT1HDAC3HDAC4HDAC1 | |
| SCHEMBL21799693 | 0.92 | SIGMAR1 (0.55) | SIGMAR1SAT1HDAC3HDAC4HDAC1 | |
| SCHEMBL21799887 | 0.92 | SIGMAR1 (0.55) | SIGMAR1SAT1HDAC3HDAC4HDAC1 | |
| SCHEMBL21799482 | 0.92 | SIGMAR1 (0.55) | SIGMAR1SAT1HDAC3HDAC4HDAC1 | |
| SCHEMBL21799707 | 0.92 | SIGMAR1 (0.55) | SIGMAR1SAT1HDAC3HDAC4HDAC1 | |
| SCHEMBL21799479 | 0.92 | SIGMAR1 (0.55) | SIGMAR1SAT1HDAC3HDAC4HDAC1 | |
| SCHEMBL21799865 | 0.92 | SIGMAR1 (0.55) | SIGMAR1SAT1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4500452-A | NOT SUBJECT TO ENZYME DEACTIVATION | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1985-02-19 | — | — | US | disclosed |
| US-4472304-A | CARCINOSTATIC | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1984-09-18 | — | — | US | disclosed |