Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 3/20 | 0.36 |
| ▸ | ACE | P12821 | 3/20 | 0.36 |
| ▸ | CPA1 | P15085 | 3/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1161012 | 0.78 | ITGB2 (0.59) | HRH4ITGB2ICAM1ITGALSLC15A2 | |
| SCHEMBL308989 | 0.78 | ITGB2 (0.59) | HRH4ITGB2ICAM1ITGALSLC15A2 | |
| SCHEMBL1229751 | 0.78 | ITGB2 (0.59) | HRH4ITGB2ICAM1ITGALSLC15A2 | |
| SCHEMBL5292853 | 0.78 | SLC7A5 (0.53) | HRH1HRH4FDPS | |
| SCHEMBL26912795 | 0.78 | SLC7A5 (0.53) | HRH1HRH4FDPS | |
| SCHEMBL1539194 | 0.78 | SLC7A5 (0.53) | HRH1HRH4FDPS | |
| SCHEMBL27469252 | 0.77 | ITGB2 (0.58) | HRH4ITGB2ICAM1ITGALSLC15A2 | |
| Hydrochloric Acid SCHEMBL28353144 | 0.77 | SLC7A5 (0.51) | HRH1HRH4FDPS | |
| SCHEMBL5598732 | 0.75 | GABRR1 (0.47) | HRH1HRH4ITGB2ICAM1ITGAL | |
| SCHEMBL31734675 | 0.75 | ACE (0.39) | CTRB1MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4529602-A | Sulfodehydroabietic acid compound | TANABE SEIYAKU CO., LTD. (JP) | 1985-07-16 | — | — | US | disclosed |
| EP-0078152-A1 | Salts of sulfodehydroabietic acid and treatment of gastro-intestinal diseases | Tanabe Seiyaku Co., Ltd. (JP) | 1983-05-04 | — | — | EP | disclosed |