Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 3/20 | 0.59 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.59 |
| ▸ | ITGAL | P20701 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.58 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1229751 | 1.00 | ITGB2 (0.59) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL308989 | 1.00 | ITGB2 (0.59) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL27469252 | 0.99 | ITGB2 (0.58) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL29368268 | 0.93 | SLC15A2 (0.53) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL28042599 | 0.90 | REN (0.61) | ITGB2ICAM1ITGALSLC15A2REN | |
| SCHEMBL21828615 | 0.90 | ITGB2 (0.57) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL27638943 | 0.90 | ITGB2 (0.57) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL29387033 | 0.88 | SLC6A5 (0.55) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL21828671 | 0.88 | CYP3A4 (0.68) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL21828702 | 0.87 | CYP3A4 (0.57) | ITGB2ICAM1ITGALCYP3A4SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105922-A1 | COMPOSITION FOR ANTI-OBESITY, BODY FAT REDUCTION OR FAT METABOLISM PROMOTION USES | プレミアアンチエイジング株式会社 | 2024-05-23 | — | — | WO | disclosed |
| EP-3328409-B1 | COMPOSITION FOR THE INCREASE OF HUMORAL SECRETION | METIS HEALTHCARE S R L (IT) | 2023-08-23 | — | — | EP | disclosed |
| US-10646476-B2 | Method for treatment of humoral secretion dysfunctions | METIS HEALTHCARE S.R.L. (IT) | 2020-05-12 | — | — | US | disclosed |
| US-20180207134-A1 | COMPOSITION FOR THE INCREASE OF HUMORAL SECRETION | METIS HEALTHCARE S.R.L. (IT) | 2018-07-26 | — | — | US | disclosed |
| EP-2459185-B1 | COMPOSITION COMPRISING ALPHA-LIPOIC ACID AND CARNOSINE FOR TREATING THE PHANTOM LIMB SYNDROME | DIFASS INTERNAT S R L (IT) | 2013-11-27 | — | — | EP | disclosed |
| EP-2459185-A1 | COMPOSITION COMPRISING ALPHA-LIPOIC ACID AND CARNOSINE FOR TREATING THE PHANTOM LIMB SYNDROME | Difass International S.r.l. (IT) | 2012-06-06 | — | — | EP | disclosed |
| US-20120129781-A1 | COMPOSITION COMPRISING ALPHA-LIPOIC ACID AND CARNOSINE FOR TREATING THE PHANTOM LIMB SYNDROME | DIFASS INTERNATIONAL S.R.L. (IT) | 2012-05-24 | — | — | US | disclosed |
| WO-2011012256-A1 | COMPOSITION COMPRISING ALPHA-LIPOIC ACID AND CARNOSINE FOR TREATING THE PHANTOM LIMB SYNDROME | DIFASS INTERNATIONAL S.R.L. (IT) | 2011-02-03 | — | — | WO | disclosed |
| WO-2008015535-A2 | COMPOSITION WITH IMPROVED ANTIOXIDANT AND ANTIGLYCATING ACTIVITY | DIFASS S.A. (SM) | 2008-02-07 | — | — | WO | disclosed |