Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154947 | 0.82 | MEN1 (0.37) | MAPK1CYP1A2CYP2C9HPGDHIF1A | |
| SCHEMBL5948823 | 0.79 | MEN1 (0.33) | ALDH1A1MEN1POLBKMT2ATSHR | |
| SCHEMBL5948658 | 0.76 | MEN1 (0.34) | MEN1POLBKMT2ATSHR | |
| SCHEMBL5948628 | 0.75 | TSHR (0.36) | ALDH1A1MEN1POLBKMT2ATSHR | |
| SCHEMBL27310498 | 0.74 | — | — | |
| SCHEMBL9714722 | 0.74 | MEN1 (0.33) | MEN1POLBKMT2A | |
| SCHEMBL5949013 | 0.73 | ESR1 (0.38) | TSHR | |
| SCHEMBL915195 | 0.73 | KCNH2 (0.37) | — | |
| Diethylaminoethanol SCHEMBL10699915 | 0.72 | — | — | |
| Diethylaminoethanol SCHEMBL3114 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056991-B1 | LIQUID DYESTUFF PREPARATIONS | CIBA-GEIGY AG (CH) | 1985-03-27 | — | — | EP | disclosed |