Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 11/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5948628 | 0.88 | TSHR (0.36) | KCNH2CA12CA1CA9PLA2G1B | |
| SCHEMBL5949013 | 0.86 | ESR1 (0.38) | KCNH2PLA2G1BPLA2G2A | |
| SCHEMBL5948888 | 0.83 | TSHR (0.36) | KCNH2PLA2G1BPLA2G2A | |
| SCHEMBL5948823 | 0.82 | MEN1 (0.33) | — | |
| SCHEMBL22725 | 0.82 | — | — | |
| SCHEMBL23451757 | 0.79 | SIGMAR1 (0.35) | KCNH2 | |
| SCHEMBL17389361 | 0.79 | TSHR (0.41) | KCNH2PLA2G1BPLA2G2A | |
| SCHEMBL5193745 | 0.79 | DNM1 (0.42) | KCNH2CA12CA1CA9KDM5A | |
| Iodide SCHEMBL5925099 | 0.79 | CA12 (0.42) | KCNH2CA12CA1CA9PLA2G1B | |
| Hydrochloric Acid SCHEMBL20494118 | 0.79 | CA12 (0.42) | KCNH2CA12CA1CA9PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7871748-B2 | Iron containing hole blocking layer containing photoconductors | XEROX CORPORATION (US) | 2011-01-18 | — | — | US | disclosed |
| US-20090035673-A1 | IRON CONTAINING HOLE BLOCKING LAYER CONTAINING PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-02-05 | — | — | US | disclosed |