Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.56 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.56 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 9/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11826491 | 0.84 | SCN1A (0.44) | ALDH1A1TSHRGLALMNAMEN1 | |
| SCHEMBL12374439 | 0.78 | ALDH1A1 (0.71) | ALDH1A1ALDH1A3ALDH3A1KDM4EPOLB | |
| SCHEMBL11524713 | 0.75 | ALDH1A1 (0.67) | ALDH1A1ALDH1A3ALDH3A1KDM4EPOLB | |
| SCHEMBL11835672 | 0.75 | GFER (0.41) | ALDH1A1KDM4EPOLBGAAGFER | |
| SCHEMBL195135 | 0.74 | ALDH1A1 (1.00) | ALDH1A1ALDH1A3ALDH3A1KDM4EPOLB | |
| SCHEMBL5733313 | 0.74 | ALDH1A1 (1.00) | ALDH1A1ALDH1A3ALDH3A1KDM4EPOLB | |
| SCHEMBL13777911 | 0.74 | TYR (0.44) | ALDH1A1ALDH1A3ALDH3A1KDM4ETSHR | |
| SCHEMBL5689109 | 0.74 | ALDH1A1 (0.59) | ALDH1A1ALDH1A3ALDH3A1KDM4EPOLB | |
| SCHEMBL10937910 | 0.73 | CYP2A6 (0.47) | ALDH1A1ALDH1A3ALDH3A1TSHRMAPT | |
| SCHEMBL10937680 | 0.72 | ALDH1A1 (0.45) | ALDH1A1ALDH1A3ALDH3A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0074569-B1 | CATIONIC METHINE DYES, PROCESS FOR THEIR PREPARATION AND THEIR USE, IN DYEING TEXTILE MATERIALS AND OTHER SUBSTRATES | BAYER AG (DE) | 1985-06-19 | — | — | EP | disclosed |
| US-4513142-A | Preparation of cationic methine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1985-04-23 | — | — | US | disclosed |