Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 19/20 | 0.70 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SHBG | P04278 | 2/20 | 0.54 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.54 |
| ▸ | SNCA | P37840 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10937828 | 1.00 | CYP19A1 (0.70) | CYP19A1OR51E2ALDH1A1LMNASHBG | |
| SCHEMBL11018536 | 0.91 | CYP19A1 (0.65) | CYP19A1OR51E2 | |
| SCHEMBL10938830 | 0.89 | CYP19A1 (0.80) | CYP19A1OR51E2 | |
| SCHEMBL10938836 | 0.89 | CYP19A1 (0.80) | CYP19A1OR51E2 | |
| SCHEMBL23743976 | 0.89 | CYP19A1 (0.80) | CYP19A1OR51E2 | |
| SCHEMBL23711134 | 0.89 | CYP19A1 (0.80) | CYP19A1OR51E2 | |
| SCHEMBL10942666 | 0.83 | CYP19A1 (0.79) | CYP19A1OR51E2 | |
| SCHEMBL10705343 | 0.83 | CYP19A1 (0.79) | CYP19A1OR51E2 | |
| SCHEMBL11017054 | 0.81 | CYP19A1 (0.69) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL10943426 | 0.81 | CYP19A1 (0.61) | CYP19A1OR51E2LMNASHBGSERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4546098-A | ANTIESTROGENS; HORMONE INHIBITORS | THE ROCKEFELLER UNIVERSITY (US) | 1985-10-08 | — | — | US | claimed |