Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 20/20 | 0.65 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10937823 | 0.91 | CYP19A1 (0.70) | CYP19A1OR51E2 | |
| SCHEMBL10937828 | 0.91 | CYP19A1 (0.70) | CYP19A1OR51E2 | |
| SCHEMBL11022288 | 0.89 | CYP19A1 (0.74) | CYP19A1OR51E2 | |
| SCHEMBL10936954 | 0.89 | CYP19A1 (0.74) | CYP19A1OR51E2 | |
| SCHEMBL10940850 | 0.81 | CYP19A1 (0.69) | CYP19A1 | |
| SCHEMBL11017054 | 0.81 | CYP19A1 (0.69) | CYP19A1 | |
| SCHEMBL23711134 | 0.80 | CYP19A1 (0.80) | CYP19A1OR51E2 | |
| SCHEMBL10938830 | 0.80 | CYP19A1 (0.80) | CYP19A1OR51E2 | |
| SCHEMBL10940369 | 0.80 | CYP19A1 (0.61) | CYP19A1OR51E2 | |
| SCHEMBL23743976 | 0.80 | CYP19A1 (0.80) | CYP19A1OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161492-A2 | Estrogen synthesis inhibitors | THE ROCKEFELLER UNIVERSITY (US) | 1985-11-21 | — | — | EP | disclosed |