Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | PRKCA | P17252 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10601278 | 0.88 | TDP1 (0.50) | MEN1KMT2AMAPTTDP1NPC1 | |
| SCHEMBL11138606 | 0.86 | MEN1 (0.68) | MEN1KMT2AMAPTTDP1NPC1 | |
| SCHEMBL13893905 | 0.86 | MEN1 (0.74) | MEN1KMT2AMAPTTDP1NPC1 | |
| SCHEMBL11115507 | 0.85 | TDP1 (0.47) | MEN1KMT2AMAPTTDP1NPC1 | |
| SCHEMBL11139628 | 0.84 | MAPT (0.49) | MEN1KMT2AMAPTTDP1NPC1 | |
| SCHEMBL10938974 | 0.84 | MAPT (0.44) | MEN1KMT2AMAPTTDP1NPC1 | |
| SCHEMBL13884828 | 0.83 | MEN1 (0.70) | MEN1KMT2AMAPTTDP1NPC1 | |
| SCHEMBL9203934 | 0.82 | MAPT (0.76) | MEN1KMT2AMAPTTDP1NPC1 | |
| SCHEMBL27626685 | 0.81 | MEN1 (0.74) | MEN1KMT2AMAPTTDP1NPC1 | |
| SCHEMBL13473993 | 0.81 | MAPT (0.67) | MEN1KMT2AMAPTTDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044666-B1 | HELICHROMIC COMPOUNDS AND DISPLAYS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-05-29 | — | — | EP | disclosed |
| US-4394070-A | Helichromic compounds and displays | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-07-19 | — | — | US | disclosed |
| EP-0044666-A2 | Helichromic compounds and displays | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1982-01-27 | — | — | EP | disclosed |