SCHEMBL9203934

SCHEMBL9203934

CCCCc1ccc(Nc2ccc(O)c3c2C(=O)c2ccccc2C3=O)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.76
▸ NPC1 O15118 3/20 0.76
▸ RAB9A P51151 3/20 0.76
▸ MEN1 O00255 3/20 0.76
▸ KMT2A Q03164 3/20 0.76
▸ LMNA P02545 2/20 0.76
▸ NPSR1 Q6W5P4 2/20 0.76
▸ TDP1 Q9NUW8 2/20 0.76
▸ MAPK1 P28482 1/20 0.76
▸ L3MBTL1 Q9Y468 1/20 0.76
▸ PRKCA P17252 2/20 0.55
▸ MTOR P42345 1/20 0.48
▸ SIRT2 Q8IXJ6 1/20 0.48
▸ MAOA P21397 1/20 0.46
▸ P2RY4 P51582 1/20 0.43
▸ CA12 O43570 2/20 0.42
▸ CA1 P00915 2/20 0.42
▸ CA2 P00918 2/20 0.42
▸ CA9 Q16790 2/20 0.42
▸ HPGD P15428 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10732288 0.92 NPC1 (0.62) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL9129626 0.91 NPC1 (0.61) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL28435986 0.89 MEN1 (0.60) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL11060750 0.88 RAB9A (0.57) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL11138606 0.88 MEN1 (0.68) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL14489853 0.87 NPC1 (0.60) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL13893905 0.87 MEN1 (0.74) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL13370284 0.86 MEN1 (1.00) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL12724013 0.85 NPC1 (0.55) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL13473966 0.85 MAPT (0.71) MAPTNPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8654290-B2 Liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2014-02-18 — — US disclosed
US-8654290-B2 Liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2014-02-18 — — US disclosed
EP-0180592-B1 LIGHT MODULATING MATERIAL COMPRISING A LIQUID CRYSTAL DISPERSION IN A SYNTHETIC RESIN MATRIX UNIV KENT STATE OHIO (US) 1995-08-02 — — EP disclosed
EP-0238626-B1 LIQUID CRYSTAL LIGHT-MODULATING MATERIALS UNIV KENT STATE OHIO (US) 1995-05-03 — — EP disclosed
EP-0238626-A4 LIQUID CRYSTAL LIGHT-MODULATING MATERIALS. UNIV KENT STATE OHIO (US) 1989-07-26 — — EP disclosed
EP-0238626-A1 LIQUID CRYSTAL LIGHT-MODULATING MATERIALS. UNIV KENT STATE OHIO (US) 1987-09-30 — — EP disclosed
US-4688900-A Light modulating material comprising a liquid crystal dispersion in a plastic matrix KENT STATE UNIVERSITY (US) 1987-08-25 — — US disclosed
WO-1987001822-A1 LIQUID CRYSTAL LIGHT-MODULATING MATERIALS KENT STATE UNIVERSITY (US) 1987-03-26 — — WO disclosed
WO-1985004262-A1 LIGHT MODULATING MATERIAL COMPRISING A LIQUID CRYSTAL DISPERSION IN A SYNTHETIC RESIN MATRIX KENT STATE UNIVERSITY (US) 1985-09-26 — — WO disclosed
US-4308163-A IMPROVING BLACK COLOR OF DICHROIC DYES GENERAL ELECTRIC COMPANY (US) 1981-12-29 — — US disclosed
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