Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10932381 | 0.82 | SRC (0.61) | HPGDCYP2C19SRCL3MBTL1CYP2C9 | |
| SCHEMBL10935441 | 0.81 | TSHR (0.55) | KMT2AMEN1CYP3A4MAPTSRC | |
| SCHEMBL10935883 | 0.81 | CA1 (0.48) | HPGDCA2CA9CA14SMN1; SMN2 | |
| SCHEMBL29247935 | 0.79 | SRC (0.64) | KMT2AMEN1HPGDCYP2C19SRC | |
| SCHEMBL10934398 | 0.78 | MAPT (0.52) | KMT2AHPGDPPARAMAPTSMN1; SMN2 | |
| SCHEMBL10890273 | 0.78 | HPGD (0.47) | KMT2AMEN1HPGDPPARAMAPT | |
| SCHEMBL2472085 | 0.77 | MEN1 (0.61) | KMT2AMEN1HPGDCYP1A2CYP2C19 | |
| SCHEMBL1059938 | 0.77 | MEN1 (0.61) | KMT2AMEN1HPGDCYP1A2CYP2C19 | |
| Acetic Acid SCHEMBL29937068 | 0.77 | SRC (0.55) | KMT2AMEN1HPGDCYP1A2CYP2C19 | |
| SCHEMBL3799753 | 0.76 | MEN1 (0.50) | KMT2AMEN1HPGDCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536400-A | VIRICIDES | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1985-08-20 | — | — | US | disclosed |
| US-4372894-A | VIRICIDES | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1983-02-08 | — | — | US | disclosed |
| EP-0003275-B1 | AROMATIC DERIVATIVES OF PHOSPHONOFORMIC ACID, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE FOR COMBATING VIRUS INFECTIONS | Astra Läkemedel Aktiebolag (SE) | 1981-09-02 | — | — | EP | disclosed |