Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10935883 | 0.85 | CA1 (0.48) | — | |
| SCHEMBL10932381 | 0.82 | SRC (0.61) | L3MBTL1SRC | |
| SCHEMBL10934398 | 0.81 | MAPT (0.52) | LMNAKMT2AMAPTL3MBTL1NPSR1 | |
| SCHEMBL10938293 | 0.81 | KMT2A (0.52) | TSHRCYP3A4MEN1KMT2AMAPT | |
| SCHEMBL27461011 | 0.79 | TSHR (0.64) | TSHRCYP3A4LMNAMEN1KMT2A | |
| SCHEMBL29247935 | 0.79 | SRC (0.64) | MEN1KMT2AL3MBTL1SRC | |
| SCHEMBL8884790 | 0.79 | TSHR (0.64) | TSHRCYP3A4LMNAMEN1KMT2A | |
| SCHEMBL157866 | 0.77 | TSHR (0.67) | TSHRCYP3A4LMNAMEN1KMT2A | |
| SCHEMBL187454 | 0.77 | TSHR (0.67) | TSHRCYP3A4LMNAMEN1KMT2A | |
| Acetic Acid SCHEMBL27794772 | 0.76 | CYP3A4 (0.79) | TSHRCYP3A4LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536400-A | VIRICIDES | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1985-08-20 | — | — | US | disclosed |
| US-4372894-A | VIRICIDES | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1983-02-08 | — | — | US | disclosed |
| EP-0003275-B1 | AROMATIC DERIVATIVES OF PHOSPHONOFORMIC ACID, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE FOR COMBATING VIRUS INFECTIONS | Astra Läkemedel Aktiebolag (SE) | 1981-09-02 | — | — | EP | disclosed |
| EP-0003275-A1 | Aromatic derivatives of phosphonoformic acid, processes for their preparation, pharmaceutical compositions containing them and their use for combating virus infections | Astra Läkemedel Aktiebolag (SE) | 1979-08-08 | — | — | EP | disclosed |