SCHEMBL10938751

SCHEMBL10938751

O=S(=O)(O)c1cccc(Nc2nc(F)nc(Nc3cc(S(=O)(=O)O)cc4cc(S(=O)(=O)O)cc(O)c34)n2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.46
FUT8 Q9BYC5 1/20 0.44
MEN1 O00255 1/20 0.43
THRB P10828 1/20 0.43
KMT2A Q03164 1/20 0.43
NSD2 O96028 1/20 0.43
DUSP3 P51452 1/20 0.43
PTPN5 P54829 1/20 0.43
CASP7 P55210 1/20 0.43
CASP6 P55212 1/20 0.43
PTPN11 Q06124 1/20 0.43
CHAT P28329 2/20 0.41
ENPP3 O14638 1/20 0.41
ENPP1 P22413 1/20 0.41
CA12 O43570 3/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA4 P22748 3/20 0.40
CA6 P23280 3/20 0.40
CA7 P43166 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16557827 0.94 NSD2 (0.41) APEX1FUT8MEN1THRBKMT2A
SCHEMBL16560634 0.92 APEX1 (0.53) APEX1FUT8MEN1THRBKMT2A
SCHEMBL5377544 0.89 FUT8 (0.55) APEX1FUT8MEN1THRBKMT2A
SCHEMBL16560585 0.89 MEN1 (0.39) APEX1FUT8MEN1THRBKMT2A
SCHEMBL11224616 0.87 APEX1 (0.49) APEX1FUT8MEN1THRBKMT2A
SCHEMBL16557815 0.86 FUT8 (0.45) APEX1FUT8MEN1THRBKMT2A
SCHEMBL11429400 0.86 CA12 (0.48) NSD2DUSP3PTPN5CASP7CASP6
SCHEMBL16560638 0.84 APEX1 (0.49) APEX1FUT8MEN1THRBKMT2A
SCHEMBL7755970 0.84 PRMT1 (0.53) MEN1THRBKMT2ANSD2DUSP3
SCHEMBL16560637 0.84 APEX1 (0.46) APEX1FUT8MEN1THRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9394445-B2 Method for continuously preparing water-soluble azo dye by coupling a nebulizer with a pipeline DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2016-07-19 US disclosed
US-20150073132-A1 METHOD FOR CONTINUOUSLY PREPARING WATER-SOLUBLE AZO DYE BY COUPLING A NEBULIZER WITH A PIPELINE DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2015-03-12 US disclosed
US-4534908-A Water-soluble disazo compounds and new bis-(aminophenoxy)-ethane compounds having fiber-reactive groups as the tetrazo components, and use of the disazo compounds as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1985-08-13 US disclosed
US-4515598-A Process for dyeing and printing fiber materials containing hydroxy and/or carbonamide groups with reactive dye containing both vinyl sulphonyl and fluoro-triazinyl groups HOECHST AKTIENGESELLSCHAFT (DE) 1985-05-07 US disclosed
EP-0071168-B1 WATER-SOLUBLE DISAZO COMPOUNDS AND BIS-(AMINO-PHENOXY)-ETHANE COMPOUNDS WITH FIBRE REACTIVE GROUPS AS TETRAZO COMPOUNDS, PROCESS FOR THE PREPARATION OF THESE COMPOUNDS AND THE USE OF THE DISAZO COMPOUNDS AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1985-01-30 EP disclosed
EP-0040790-A2 Process for dyeing and printing textile materials containing hydroxyl and/or carbon-amide groups HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-02 EP disclosed