SCHEMBL5377544

SCHEMBL5377544

O=S(=O)(O)c1cccc(Nc2nc(Cl)nc(Nc3cc(S(=O)(=O)O)cc4cc(S(=O)(=O)O)cc(O)c34)n2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FUT8 Q9BYC5 1/20 0.55
CHAT P28329 3/20 0.51
ENPP3 O14638 1/20 0.51
ENPP1 P22413 1/20 0.51
CA12 O43570 6/20 0.47
CA1 P00915 6/20 0.47
CA2 P00918 6/20 0.47
CA9 Q16790 6/20 0.47
APEX1 P27695 2/20 0.46
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
THRB P10828 1/20 0.43
NSD2 O96028 1/20 0.43
DUSP3 P51452 1/20 0.43
PTPN5 P54829 1/20 0.43
CASP7 P55210 1/20 0.43
CASP6 P55212 1/20 0.43
PTPN11 Q06124 1/20 0.43
USP2 O75604 1/20 0.42
NFKB1 P19838 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16557849 0.94 FUT8 (0.51) FUT8CHATENPP3ENPP1CA12
SCHEMBL16560635 0.92 FUT8 (0.60) FUT8CHATENPP3ENPP1CA12
SCHEMBL14290717 0.90 FUT8 (0.50) FUT8CHATENPP3ENPP1CA12
SCHEMBL9233802 0.89 FUT8 (0.53) FUT8CHATENPP3ENPP1CA12
SCHEMBL19004091 0.89 FUT8 (0.58) FUT8CHATENPP3ENPP1CA12
SCHEMBL10938751 0.89 APEX1 (0.46) FUT8CHATENPP3ENPP1CA12
SCHEMBL13599493 0.89 FUT8 (0.46) FUT8CHATENPP3ENPP1CA12
SCHEMBL16560587 0.89 FUT8 (0.46) FUT8CHATENPP3ENPP1CA12
SCHEMBL5702813 0.87 FUT8 (0.50) FUT8CHATENPP3ENPP1CA12
SCHEMBL30528721 0.87 FUT8 (0.50) FUT8CHATENPP3ENPP1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020055619-A1 Process for preparing azo colorants CLARIANT GMBH 2002-05-09 US claimed
EP-1195411-A1 Process for the preparation of azo colourants Clariant GmbH (DE) 2002-04-10 EP claimed
US-9394445-B2 Method for continuously preparing water-soluble azo dye by coupling a nebulizer with a pipeline DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2016-07-19 US disclosed
US-20150073132-A1 METHOD FOR CONTINUOUSLY PREPARING WATER-SOLUBLE AZO DYE BY COUPLING A NEBULIZER WITH A PIPELINE DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2015-03-12 US disclosed
US-7309389-B2 Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias CLARIANT FINANCE (BVI) LIMITED (VG) 2007-12-18 US disclosed
US-7135266-B2 Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias CLARIANT FINANCE (BVI) LIMITED (VG) 2006-11-14 US disclosed
US-20060228640-A1 Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias CLARIANT FINANCE (BVI) LIMITED 2006-10-12 US disclosed
US-20060042117-A1 Method and device for carrying out chemical and physical methods CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2006-03-02 US disclosed
EP-1558682-A1 METHOD AND DEVICE FOR CARRYING OUT CHEMICAL AND PHYSICAL METHODS Clariant GmbH (DE) 2005-08-03 EP disclosed
EP-1363975-B1 METHOD AND DEVICE FOR CONTINUOUS REDOX ADJUSTMENT IN AZOIC COUPLINGS CLARANT GMBH (DE) 2005-03-30 EP disclosed
US-20040131507-A1 Adjustment of concentration of reactants; rotating electrodes transverse to fluid flow; process control SAITMACHER KLAUS (DE) 2004-07-08 US disclosed
EP-0675172-B1 Water-solable azo compounds, process for their preparation and their use as dyestuffs DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-04-11 EP disclosed
EP-0681008-B1 Black mixtures of reactive azo dyes and their use for dyeing fibrous material containing hydroxy and/or carbonamide groups DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-02-14 EP disclosed
EP-1054043-A2 Orange and scarlet coloured mixtures of reactive dyes DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2000-11-22 EP disclosed
US-5559215-A Black mixture of fibre-reactive azo dyes containing essentially a navy-blue disazo dye and an orange monoazo dye, as well as novel fibre-reactive phenylazonaphthol dyes containing A 2-(2'-sufophenylamino)-4-fluoro-1,3,5-triazin-6-ylamino group HOECHST AKTIENGESELLSCHAFT (DE) 1996-09-24 US disclosed
EP-0679697-A2 Black mixtures of reactive azo dyes and their use for dyeing fibrous material containing hydroxy and/or carbonamide groups HOECHST AKTIENGESELLSCHAFT (DE) 1995-11-02 EP disclosed
EP-0675172-A2 Water-solable azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-04 EP disclosed
US-4534908-A Water-soluble disazo compounds and new bis-(aminophenoxy)-ethane compounds having fiber-reactive groups as the tetrazo components, and use of the disazo compounds as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1985-08-13 US disclosed
EP-0071168-B1 WATER-SOLUBLE DISAZO COMPOUNDS AND BIS-(AMINO-PHENOXY)-ETHANE COMPOUNDS WITH FIBRE REACTIVE GROUPS AS TETRAZO COMPOUNDS, PROCESS FOR THE PREPARATION OF THESE COMPOUNDS AND THE USE OF THE DISAZO COMPOUNDS AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1985-01-30 EP disclosed
EP-0071168-A2 Water-soluble disazo compounds and bis-(amino-phenoxy)-ethane compounds with fibre reactive groups as tetrazo compounds, process for the preparation of these compounds and the use of the disazo compounds as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1983-02-09 EP disclosed