Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FFAR2 | O15552 | 9/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066121 | 1.00 | ACE (0.66) | ACELMNAFFAR2HTTALDH1A1 | |
| SCHEMBL10968302 | 0.88 | ACE (0.67) | ACELMNAFFAR2HTTALDH1A1 | |
| SCHEMBL11061441 | 0.87 | HSD17B10 (0.49) | ACELMNAFFAR2ALDH1A1POLB | |
| SCHEMBL11096479 | 0.85 | ACE (0.64) | ACELMNAFFAR2HTTALDH1A1 | |
| SCHEMBL10939320 | 0.85 | ACE (0.52) | ACELMNAFFAR2HPGD | |
| SCHEMBL11110329 | 0.85 | ACE (0.48) | ACELMNAFFAR2HTT | |
| SCHEMBL11293550 | 0.84 | ACE (0.51) | ACELMNAFFAR2HTTALDH1A1 | |
| SCHEMBL10939290 | 0.84 | ACE (0.51) | ACELMNAFFAR2HTTALDH1A1 | |
| SCHEMBL11067697 | 0.82 | ACE (0.43) | ACELMNAFFAR2HTTALDH1A1 | |
| SCHEMBL11063036 | 0.82 | ACE (0.82) | ACELMNAFFAR2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048763-B1 | SULFUR-CONTAINING ACYLAMINO ACIDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1985-11-06 | — | — | EP | disclosed |
| EP-0067885-B1 | HETEROCYCLIC 5-MEMBERED RING COMPOUNDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1985-09-04 | — | — | EP | disclosed |
| US-4464371-A | HYPOTENSIVE AGENTS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-08-07 | — | — | US | disclosed |
| US-4425333-A | HYPOTENSIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-01-10 | — | — | US | disclosed |
| EP-0067885-A1 | HETEROCYCLIC 5-MEMBERED RING COMPOUNDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-12-29 | — | — | EP | disclosed |
| EP-0048763-A1 | SULFUR-CONTAINING ACYLAMINO ACIDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-04-07 | — | — | EP | disclosed |