Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | FFAR2 | O15552 | 12/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10938818 | 0.85 | ACE (0.66) | ACEFFAR2HTTLMNA | |
| SCHEMBL11066121 | 0.85 | ACE (0.66) | ACEFFAR2HTTLMNA | |
| SCHEMBL11110323 | 0.84 | FFAR2 (0.47) | ACEFFAR2HTTLMNA | |
| SCHEMBL11102513 | 0.82 | ACE (0.68) | ACEFFAR2HTTLMNA | |
| SCHEMBL11110326 | 0.81 | ACE (0.51) | ACEFFAR2HTTLMNA | |
| SCHEMBL11075099 | 0.81 | FFAR2 (0.54) | ACEFFAR2HTTLMNA | |
| SCHEMBL10995341 | 0.80 | ACE (0.44) | ACEFFAR2HTTLMNA | |
| SCHEMBL11061441 | 0.80 | HSD17B10 (0.49) | ACEFFAR2LMNA | |
| SCHEMBL11267042 | 0.79 | ACE (0.53) | ACEFFAR2HTTLMNA | |
| SCHEMBL10999357 | 0.76 | ACE (0.49) | ACEFFAR2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4457935-A | ANGIOTENSIN-CONVERTING ENZYME INHIBITOR | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-07-03 | — | — | US | claimed |