SCHEMBL10939656

SCHEMBL10939656

O=[N+]([O-])c1cscc1[N+](=O)[O-]

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 7/20 0.42
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41
CES1 P23141 1/20 0.41
GPR35 Q9HC97 2/20 0.40
HSD17B10 Q99714 1/20 0.39
TXNRD1 Q16881 1/20 0.38
TXNRD3 Q86VQ6 1/20 0.38
TXNRD2 Q9NNW7 1/20 0.38
CYP3A4 P08684 3/20 0.37
TSHR P16473 3/20 0.37
MAPT P10636 2/20 0.37
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
HPGD P15428 1/20 0.37
GRIK1 P39086 1/20 0.37
GRIA1 P42261 1/20 0.37
GRIA2 P42262 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16289532 0.82
SCHEMBL8149711 0.82
SCHEMBL16289531 0.82
SCHEMBL826681 0.82
SCHEMBL3622560 0.82
SCHEMBL15741276 0.82
SCHEMBL5114836 0.77 ALDH1A1 (0.38) TDP1GPR35TSHRMAPTCYP1A2
SCHEMBL29163586 0.77 TSHR (0.46) TDP1GPR35CYP3A4TSHRMAPT
SCHEMBL8688932 0.69 TSHR (0.55) TDP1GPR35HSD17B10CYP3A4TSHR
SCHEMBL22566 0.65 HSD17B10 (0.67) TDP1GPR35HSD17B10TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178680-A D-A type polymer based on 2,1, 3-benzothiadiazole-5, 6-dicarboxylic acid imide and preparation method and application thereof 湖南工程学院 2023-05-30 CN claimed
CN-116178680-A D-A type polymer based on 2,1, 3-benzothiadiazole-5, 6-dicarboxylic acid imide and preparation method and application thereof 湖南工程学院 2023-05-30 CN disclosed
CN-100540554-C Novel compounds capable of being used in organic layers of organic light emitting devices LG CHEMICAL LTD (KR) 2009-09-16 CN disclosed
CN-1863890-A Novel compounds capable of being used in organic layers of organic light emitting devices LG CHEMICAL LTD (KR) 2006-11-15 CN disclosed
US-4582947-A Nucleophilic displacement process for preparing 2,6-dihydrocarbonyl-4-(nitroaryl)phenol ETHYL CORPORATION (US) 1986-04-15 US disclosed