Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 4/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8752529 | 0.85 | EGFR (0.45) | KDM4ETDP1EGFRBCHEACHE | |
| Acrylic Acid SCHEMBL29184857 | 0.85 | KDM4E (0.49) | KDM4ETDP1TSHRHPGDEGFR | |
| SCHEMBL28053687 | 0.84 | EGFR (0.40) | TDP1EGFRAKR1B10AKR1B1BCHE | |
| Styrene SCHEMBL10612528 | 0.83 | TSHR (0.49) | TDP1TSHRHPGDLMNAL3MBTL1 | |
| Acrylic Acid Ethyl Ester SCHEMBL5153322 | 0.83 | TSHR (0.48) | KDM4ETDP1TSHRHPGDEGFR | |
| Acrylic Acid Methyl Ester SCHEMBL10706577 | 0.83 | KDM4E (0.48) | KDM4ETDP1TSHRHPGDEGFR | |
| SCHEMBL29394 | 0.83 | KDM4E (0.53) | KDM4ETDP1TSHREGFRAKR1B10 | |
| Maleic Acid SCHEMBL11028703 | 0.82 | KDM4E (0.50) | KDM4ETDP1TSHREGFRBCHE | |
| Butadiene SCHEMBL10718191 | 0.82 | KDM4E (0.50) | KDM4ETDP1TSHREGFRAKR1B10 | |
| SCHEMBL10905565 | 0.82 | TSHR (0.44) | KDM4ETDP1TSHRHPGDEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4520088-A | COPOLYMER OF A STYRENE, AN ALKYL ACRYLATE WITH A C-4 OR GREATER ALKYL, AND A C-3 OR SMALLER ALKYL ACRYLATE | MITSUBISHI PAPER MILLS, LTD. (JP) | 1985-05-28 | — | — | US | disclosed |