SCHEMBL28053687

SCHEMBL28053687

C=CC(=O)OC(CC)CCCCC.COOC(=O)C=Cc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
LMNA P02545 1/20 0.39
HDAC3 O15379 1/20 0.38
AKR1B10 O60218 1/20 0.38
AKR1B1 P15121 1/20 0.38
CTSL P07711 1/20 0.37
CTSB P07858 1/20 0.37
CTSK P43235 1/20 0.37
THRA P10827 1/20 0.37
THRB P10828 1/20 0.37
MMP1 P03956 1/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TUBB4A P04350 2/20 0.35
TUBB P07437 2/20 0.35
TUBA3C P0DPH7 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3222436 0.86 EGFR (0.49) EGFRTDP1LMNAHDAC3AKR1B10
SCHEMBL3222440 0.86 EGFR (0.49) EGFRTDP1LMNAHDAC3AKR1B10
SCHEMBL119065 0.85 EGFR (0.51) EGFRTDP1LMNAHDAC3AKR1B10
Styrene SCHEMBL9013506 0.84 THRB (0.42) CTSLCTSBCTSKTHRATHRB
SCHEMBL10940583 0.84 KDM4E (0.40) EGFRTDP1LMNAAKR1B10AKR1B1
Styrene SCHEMBL15709264 0.82 CTSK (0.41) CTSLCTSBCTSKTHRATHRB
3-Octanol SCHEMBL28795848 0.82 EGFR (0.45) EGFRTDP1LMNAHDAC3AKR1B10
SCHEMBL28474356 0.82 EGFR (0.47) EGFRTDP1LMNAHDAC3AKR1B10
SCHEMBL2351974 0.82 CTSK (0.37) EGFRTDP1LMNAHDAC3CTSL
Octane SCHEMBL28761136 0.81 EGFR (0.57) EGFRTDP1LMNAHDAC3AKR1B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105342945-A Fleece care solution TONGLING BAIRUI EQUIPMENT PARTS CO LTD 2016-02-24 CN disclosed