Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10943203 | 0.97 | ACE (0.53) | ACETBXA2RLMNATERTCYP1A2 | |
| SCHEMBL8398562 | 0.89 | ACE (0.56) | ACEHTTLMNATERTFFAR2 | |
| SCHEMBL8654100 | 0.88 | ACE (0.70) | ACEHTTLMNATERTFFAR2 | |
| SCHEMBL10941007 | 0.83 | ACE (0.77) | ACEHTTLMNAFFAR2ALDH1A1 | |
| SCHEMBL10940664 | 0.80 | ACE (0.75) | ACETBXA2RHTTLMNAFFAR2 | |
| SCHEMBL11004289 | 0.75 | ACE (0.80) | ACEHTTLMNAFFAR2ALDH1A1 | |
| SCHEMBL10944184 | 0.75 | ACE (0.80) | ACEHTTLMNAFFAR2ALDH1A1 | |
| SCHEMBL10943539 | 0.75 | ACE (0.46) | ACE | |
| SCHEMBL10943414 | 0.74 | ACE (0.41) | ACETERT | |
| SCHEMBL683207 | 0.73 | ACE (0.87) | ACEHTTLMNAFFAR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031104-B1 | THIAZOLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1985-10-23 | — | — | EP | claimed |