Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10941015 | 0.97 | ACE (0.54) | ACETBXA2RHTR2CSLC6A3LMNA | |
| SCHEMBL8654100 | 0.87 | ACE (0.70) | ACELMNATERTFFAR2ALDH1A1 | |
| SCHEMBL10940664 | 0.83 | ACE (0.75) | ACETBXA2RLMNAFFAR2ALDH1A1 | |
| SCHEMBL10941007 | 0.80 | ACE (0.77) | ACELMNAFFAR2ALDH1A1POLB | |
| SCHEMBL11004289 | 0.79 | ACE (0.80) | ACELMNAFFAR2ALDH1A1POLB | |
| SCHEMBL10945948 | 0.76 | PTGFR (0.39) | DRD3 | |
| SCHEMBL10945129 | 0.75 | L3MBTL1 (0.43) | KMT2ALMNAALDH1A1POLB | |
| SCHEMBL10944184 | 0.75 | ACE (0.80) | ACELMNAFFAR2ALDH1A1POLB | |
| SCHEMBL10943539 | 0.74 | ACE (0.46) | ACE | |
| SCHEMBL10943414 | 0.74 | ACE (0.41) | ACETERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031104-B1 | THIAZOLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1985-10-23 | — | — | EP | claimed |