Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10938704 | 0.95 | PLA2G2A (0.43) | PLA2G2APLA2G10PLA2G1BPLA2G5TSHR | |
| SCHEMBL10940564 | 0.93 | PLA2G2A (0.43) | PLA2G2APLA2G10PLA2G1BPLA2G5TSHR | |
| SCHEMBL10939717 | 0.91 | PLA2G2A (0.42) | PLA2G2APLA2G10PLA2G1BPLA2G5TSHR | |
| SCHEMBL10942611 | 0.91 | PLA2G2A (0.44) | PLA2G2APLA2G10PLA2G1BPLA2G5TSHR | |
| SCHEMBL11129254 | 0.91 | PLA2G2A (0.44) | PLA2G2APLA2G10PLA2G1BPLA2G5TSHR | |
| SCHEMBL10944558 | 0.91 | PLA2G2A (0.44) | PLA2G2APLA2G10PLA2G1BPLA2G5TSHR | |
| SCHEMBL10937042 | 0.91 | PLA2G2A (0.44) | PLA2G2APLA2G10PLA2G1BPLA2G5TSHR | |
| SCHEMBL10940306 | 0.91 | PLA2G2A (0.44) | PLA2G2APLA2G10PLA2G1BPLA2G5TSHR | |
| SCHEMBL10946092 | 0.91 | PLA2G2A (0.44) | PLA2G2APLA2G10PLA2G1BPLA2G5TSHR | |
| SCHEMBL10938464 | 0.90 | TLR2 (0.44) | PLA2G2APLA2G10PLA2G1BPLA2G5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0070433-B1 | PHOSPHOLIPID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION OF THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |
| US-4493832-A | HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-01-15 | — | — | US | disclosed |
| EP-0070433-A1 | Phospholipid derivatives, processes for preparation thereof and pharmaceutical composition of the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-01-26 | — | — | EP | disclosed |