Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL717516 | 0.87 | ELANE (0.76) | ELANEKMT2AMEN1HSD17B10MAPT | |
| SCHEMBL10943195 | 0.81 | ELANE (0.61) | ELANEKMT2AMEN1HSD17B10MAPT | |
| SCHEMBL1088052 | 0.79 | LMNA (0.65) | ELANEKMT2AMEN1HSD17B10MAPT | |
| SCHEMBL1590016 | 0.77 | ELANE (1.00) | ELANEKMT2AMEN1HSD17B10MAPT | |
| SCHEMBL9339013 | 0.76 | ELANE (0.83) | ELANEKMT2AMEN1HSD17B10MAPT | |
| SCHEMBL17928622 | 0.76 | USP2 (0.56) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL21629507 | 0.76 | ELANE (0.64) | ELANEKMT2AMEN1HSD17B10MAPT | |
| SCHEMBL31018937 | 0.76 | ELANE (0.81) | ELANEKMT2AMEN1HSD17B10MAPT | |
| SCHEMBL269329 | 0.76 | LMNA (0.80) | ELANEKMT2AMEN1HSD17B10MAPT | |
| Acetic Acid Phenyl Ester SCHEMBL3418961 | 0.74 | ELANE (0.67) | ELANEKMT2AMEN1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4529556-A | Aryl substituted with hydroxy, epoxy or glycidyl groups | THE DOW CHEMICAL COMPANY (US) | 1985-07-16 | — | — | US | disclosed |