Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 4/20 | 0.52 |
| ▸ | MME | P08473 | 2/20 | 0.48 |
| ▸ | EED | O75530 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10941503 | 1.00 | PSMB5 (0.52) | PSMB5MMEEED | |
| SCHEMBL10940198 | 0.89 | REN (0.51) | PSMB5 | |
| SCHEMBL10949165 | 0.88 | PSMB5 (0.56) | PSMB5MMEEED | |
| SCHEMBL10949155 | 0.88 | PSMB5 (0.56) | PSMB5MMEEED | |
| SCHEMBL9069586 | 0.87 | MME (0.55) | PSMB5MMEEED | |
| SCHEMBL9069587 | 0.87 | MME (0.55) | PSMB5MMEEED | |
| SCHEMBL9068941 | 0.84 | PSMB5 (0.59) | PSMB5MMEEED | |
| SCHEMBL10736781 | 0.84 | PSMB5 (0.59) | PSMB5MMEEED | |
| SCHEMBL9068940 | 0.84 | PSMB5 (0.59) | PSMB5MMEEED | |
| SCHEMBL10737452 | 0.84 | PSMB5 (0.59) | PSMB5MMEEED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4560506-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1985-12-24 | — | — | US | disclosed |