Sulfuric Acid

Sulfuric Acid

SCHEMBL10941663

O=S(=O)(O)O.ONc1ccccc1

nearest known ligand 0.74

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.74
ACP1 P24666 2/20 0.48
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
KEAP1 Q14145 2/20 0.46
MMP1 P03956 2/20 0.46
MMP2 P08253 2/20 0.46
MMP9 P14780 2/20 0.46
MMP8 P22894 2/20 0.46
MMP13 P45452 2/20 0.46
TSHR P16473 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
IL1RN P18510 1/20 0.44
ERAP1 Q9NZ08 1/20 0.44
TP53 P04637 1/20 0.44
EPHX1 P07099 1/20 0.44
EPHX2 P34913 1/20 0.44
CDK9 P50750 1/20 0.44
CLK4 Q9HAZ1 1/20 0.44
ALDH1A1 P00352 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL98310 0.86
SCHEMBL29494117 0.83
SCHEMBL28117000 0.83
SCHEMBL27906839 0.83
SCHEMBL2531299 0.83
SCHEMBL1244278 0.83
Hydrochloric Acid SCHEMBL874033 0.83
Ammonia Solution, Strong SCHEMBL5177854 0.83
Lithium SCHEMBL29701325 0.83
SCHEMBL28325212 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103170083-A Fire extinguishing composition containing transition metal compound SHAANXI J & R FIRE FIGHTING CO 2013-06-26 CN claimed
CN-103170083-B Fire extinguishing composition containing transition metal compound XI'AN J & R FIRE FIGHTING EQUIPMENT Co.,Ltd. (CN) 2016-04-06 CN disclosed
CN-103170083-A Fire extinguishing composition containing transition metal compound SHAANXI J & R FIRE FIGHTING CO 2013-06-26 CN disclosed
EP-0085890-B1 PROCESS FOR PREPARING P-AMINOPHENOL AND ALKYL SUBSTITUTED P-AMINOPHENOL MALLINCKRODT, INC.(a Missouri corporation) (US) 1985-11-27 EP disclosed
US-4415753-A INCREASING THE HYDROGENATION CATALYST SELECTIVITY BY INCLUDING AN ORGANIC SULFUR COMPOUND MALLINCKRODT, INC. (US) 1983-11-15 US disclosed
EP-0085890-A1 Process for preparing p-aminophenol and alkyl substituted p-aminophenol MALLINCKRODT, INC.(a Missouri corporation) (US) 1983-08-17 EP disclosed