Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ACE | P12821 | 16/20 | 0.59 |
| ▸ | ACE2 | Q9BYF1 | 10/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10942263 | 1.00 | TSHR (0.60) | TSHRACEACE2 | |
| SCHEMBL10944362 | 1.00 | TSHR (0.60) | TSHRACEACE2 | |
| SCHEMBL10944342 | 1.00 | TSHR (0.60) | TSHRACEACE2 | |
| SCHEMBL10940307 | 0.89 | ACE (0.58) | TSHRACEACE2 | |
| SCHEMBL10940312 | 0.89 | ACE (0.58) | TSHRACEACE2 | |
| SCHEMBL10942786 | 0.89 | ACE (0.58) | TSHRACEACE2 | |
| SCHEMBL10942781 | 0.89 | ACE (0.58) | TSHRACEACE2 | |
| SCHEMBL10830758 | 0.82 | TSHR (0.62) | TSHRACEACE2 | |
| SCHEMBL15251975 | 0.82 | ACE (0.70) | TSHRACEACE2 | |
| SCHEMBL10830200 | 0.82 | TSHR (0.62) | TSHRACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4500467-A | ANGIOTENSIN INHIBITORS, HYPOTENSIVE AGENTS | BASF AKTIENGESELLSCAFT (DE) | 1985-02-19 | — | — | US | disclosed |
| EP-0110224-A2 | Benzoylthio compounds, their manufacture and use as medicines | BASF Aktiengesellschaft (DE) | 1984-06-13 | — | — | EP | disclosed |