Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 14/20 | 0.58 |
| ▸ | ACE2 | Q9BYF1 | 6/20 | 0.58 |
| ▸ | PREP | P48147 | 1/20 | 0.52 |
| ▸ | FAP | Q12884 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10942781 | 1.00 | ACE (0.58) | ACEACE2PREPFAPTSHR | |
| SCHEMBL10940307 | 1.00 | ACE (0.58) | ACEACE2PREPFAPTSHR | |
| SCHEMBL10942786 | 1.00 | ACE (0.58) | ACEACE2PREPFAPTSHR | |
| SCHEMBL10944362 | 0.89 | TSHR (0.60) | ACEACE2TSHR | |
| SCHEMBL10944342 | 0.89 | TSHR (0.60) | ACEACE2TSHR | |
| SCHEMBL10942254 | 0.89 | TSHR (0.60) | ACEACE2TSHR | |
| SCHEMBL10942263 | 0.89 | TSHR (0.60) | ACEACE2TSHR | |
| SCHEMBL10733989 | 0.86 | ACE (0.64) | ACEACE2PREPFAPTSHR | |
| SCHEMBL10731797 | 0.86 | ACE (0.64) | ACEACE2PREPFAPTSHR | |
| SCHEMBL10940703 | 0.86 | ACE (0.49) | ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4500467-A | ANGIOTENSIN INHIBITORS, HYPOTENSIVE AGENTS | BASF AKTIENGESELLSCAFT (DE) | 1985-02-19 | — | — | US | disclosed |
| EP-0110224-A2 | Benzoylthio compounds, their manufacture and use as medicines | BASF Aktiengesellschaft (DE) | 1984-06-13 | — | — | EP | disclosed |