Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.55 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 3/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CTH | P32929 | 1/20 | 0.42 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.41 |
| ▸ | GLRB | P48167 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807152 | 0.98 | HMGB1 (0.56) | HMGB1CXCL12RXRBAKR1C2AKR1C1 | |
| SCHEMBL28717119 | 0.88 | AKR1C2 (0.53) | HMGB1CXCL12RXRBAKR1C2AKR1C1 | |
| SCHEMBL10462619 | 0.86 | HMGB1 (0.56) | HMGB1CXCL12RXRBAKR1C2AKR1C1 | |
| SCHEMBL29090571 | 0.83 | NR5A2 (0.54) | RXRBAKR1C2AKR1C1ALDH1A1TDP1 | |
| SCHEMBL828961 | 0.83 | NR5A2 (0.54) | RXRBAKR1C2AKR1C1ALDH1A1TDP1 | |
| SCHEMBL11756982 | 0.82 | AKR1C2 (0.49) | HMGB1CXCL12RXRBAKR1C2AKR1C1 | |
| SCHEMBL10469464 | 0.82 | GABRA1 (0.41) | HMGB1CXCL12RXRBAKR1C2KDM4E | |
| Water SCHEMBL9343049 | 0.81 | NR5A2 (0.52) | RXRBAKR1C2AKR1C1ALDH1A1TDP1 | |
| SCHEMBL29193193 | 0.81 | NR5A2 (0.52) | RXRBAKR1C2AKR1C1ALDH1A1TDP1 | |
| SCHEMBL7087887 | 0.81 | HMGB1 (0.47) | HMGB1CXCL12AKR1C2AKR1C1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59100174-A | — | — | None | — | — | JP | disclosed |
| US-4557618-A | PHENOLIC DEVELOPER AND ELECTRON DONATING COLORLESS DYE; DESENSITIZING COMPOUND | PENTEL KABUSHIKI KAISHA (JP) | 1985-12-10 | — | — | US | disclosed |
| JP-S59100174-A | ERASABLE COLORLESS DYE/DEVELOPER INK | PENTEL KK | 1984-06-09 | — | — | JP | disclosed |