Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10942642 | 0.97 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL10945023 | 0.93 | KDM4E (0.55) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL10946013 | 0.91 | KDM4E (0.55) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL10948788 | 0.79 | NPC1 (0.48) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL10944725 | 0.79 | CYP1A2 (0.37) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL10942256 | 0.78 | KDM4E (0.42) | ALDH1A1KDM4EMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL10941723 | 0.77 | NPC1 (0.51) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL10945783 | 0.77 | ALDH1A1 (0.39) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL10944017 | 0.75 | KDM4E (0.42) | ALDH1A1KDM4EMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL11362698 | 0.75 | CA12 (0.42) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496447-A | PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS AND FOR CURING PRINTING INKS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1985-01-29 | — | — | US | disclosed |
| US-4374984-A | Aromatic-aliphatic ketones useful as photoinitiators | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-02-22 | — | — | US | disclosed |