Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.75 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.75 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.75 |
| ▸ | GAA | P10253 | 1/20 | 0.75 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.75 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.75 |
| ▸ | HTT | P42858 | 1/20 | 0.75 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.75 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.75 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.75 |
| ▸ | TP53 | P04637 | 1/20 | 0.75 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.74 |
| ▸ | THPO | P40225 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11881650 | 0.94 | TSHR (0.72) | TSHRPMP22ADORA2AADORA3GAA | |
| SCHEMBL9352957 | 0.89 | MEN1 (0.76) | TSHRPMP22ADORA2AADORA3GAA | |
| SCHEMBL9352946 | 0.89 | MEN1 (0.76) | TSHRPMP22ADORA2AADORA3GAA | |
| SCHEMBL23982261 | 0.88 | ADORA1 (0.92) | TSHRPMP22ADORA2AADORA3GAA | |
| SCHEMBL9495163 | 0.88 | ADORA1 (0.92) | TSHRPMP22ADORA2AADORA3GAA | |
| SCHEMBL9495177 | 0.88 | ADORA1 (0.92) | TSHRPMP22ADORA2AADORA3GAA | |
| SCHEMBL9142235 | 0.88 | ADORA1 (0.92) | TSHRPMP22ADORA2AADORA3GAA | |
| SCHEMBL11013427 | 0.86 | TSHR (0.69) | TSHRPMP22ADORA2AADORA3GAA | |
| N6-Cyclopentyladenosine SCHEMBL472621 | 0.86 | ADORA3 (1.00) | TSHRPMP22ADORA2AADORA3GAA | |
| SCHEMBL9793271 | 0.86 | ADORA3 (0.96) | TSHRPMP22ADORA2AADORA3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4501735-A | HYPOTENSIVE AGENTS | WARNER-LAMBERT COMPANY (US) | 1985-02-26 | — | — | US | disclosed |