Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11749020 | 0.83 | ALDH1A1 (0.57) | ALDH1A1GAASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL12417061 | 0.82 | — | — | |
| SCHEMBL766360 | 0.80 | — | — | |
| SCHEMBL28521894 | 0.75 | ALDH1A1 (0.55) | ALDH1A1GAASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6382888 | 0.73 | ALDH1A1 (0.49) | ALDH1A1GAASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10944712 | 0.73 | ALDH1A1 (0.49) | ALDH1A1GAASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28299002 | 0.73 | — | — | |
| SCHEMBL9717857 | 0.72 | ALDH1A1 (0.47) | ALDH1A1GAASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL14893122 | 0.72 | ALDH1A1 (0.47) | ALDH1A1GAASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL891457 | 0.72 | ALDH1A1 (0.55) | ALDH1A1GAASLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4515920-A | Synthesis of peptides and proteins | THE ROCKEFELLER UNIVERSITY (US) | 1985-05-07 | — | — | US | disclosed |