Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10944580 | 0.94 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2TSHRMAPK1HPGD | |
| SCHEMBL10943297 | 0.93 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2TSHRMAPK1HPGD | |
| SCHEMBL10941099 | 0.91 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2TSHRMAPK1HPGD | |
| SCHEMBL9681708 | 0.91 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2TSHRMAPK1HPGD | |
| SCHEMBL9681137 | 0.89 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2TSHRMAPK1HPGD | |
| SCHEMBL10945183 | 0.88 | CES1 (0.44) | ALDH1A1SMN1; SMN2CES1KMT2AMAPK14 | |
| SCHEMBL10942634 | 0.87 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2TSHRMAPK1HPGD | |
| SCHEMBL10942591 | 0.85 | HPGD (0.61) | ALDH1A1SMN1; SMN2TSHRMAPK1HPGD | |
| SCHEMBL9679962 | 0.84 | HPGD (0.62) | ALDH1A1SMN1; SMN2TSHRMAPK1HPGD | |
| SCHEMBL10943047 | 0.84 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2TSHRMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496447-A | PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS AND FOR CURING PRINTING INKS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1985-01-29 | — | — | US | disclosed |
| US-4374984-A | Aromatic-aliphatic ketones useful as photoinitiators | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-02-22 | — | — | US | disclosed |