Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30599557 | 0.84 | MAPT (0.66) | HPGDALOX15MEN1KMT2ATDP1 | |
| SCHEMBL1189665 | 0.84 | MAPT (0.66) | HPGDALOX15MEN1KMT2ATDP1 | |
| SCHEMBL15741927 | 0.83 | HPGD (0.76) | HPGDALOX15MEN1KMT2ATDP1 | |
| SCHEMBL10711553 | 0.83 | HPGD (0.76) | HPGDALOX15MEN1KMT2ATDP1 | |
| SCHEMBL11884789 | 0.83 | HPGD (0.76) | HPGDALOX15MEN1KMT2ATDP1 | |
| SCHEMBL5155416 | 0.82 | HPGD (0.74) | HPGDALOX15MEN1KMT2ATDP1 | |
| SCHEMBL1412533 | 0.82 | HPGD (0.74) | HPGDALOX15MEN1KMT2ATDP1 | |
| Chlorpropham SCHEMBL11299029 | 0.82 | HPGD (0.89) | HPGDALOX15MEN1KMT2ATDP1 | |
| SCHEMBL31073677 | 0.82 | HPGD (0.74) | HPGDALOX15MEN1KMT2ATDP1 | |
| Chlorpropham SCHEMBL22437601 | 0.82 | HPGD (1.00) | HPGDALOX15MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4515619-A | 1,2,3-Thiadiazole-5-yl-urea derivatives, agents containing these compounds with plant growth regulating and defoliating activity | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-05-07 | — | — | US | disclosed |
| US-4491466-A | 1,2,3-Thiadiazole-5-yl-urea derivatives, processes for their use as plant growth regulating and defoliating agents | SCHERING AG (DE) | 1985-01-01 | — | — | US | disclosed |
| US-4261726-A | OR DEFOLIATION; UREA OR THIOUREA DERIVATIVE OF 1,2,3-THIADIAZOLE | SCHERING AG (DE) | 1981-04-14 | — | — | US | disclosed |
| US-4243404-A | 1,2,3-Thiadiazole-3-in-5-ylidene-urea derivatives, process for making the same and compositions containing the same having growth regulating activity for plants | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-01-06 | — | — | US | disclosed |
| US-4181517-A | 1,2,3-Thiadiazole-2-id derivatives, process for making the same and composition containing the same having a growth regulating activity for plants | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-01-01 | — | — | US | disclosed |
| US-4177054-A | PREEMERGENT AND POSTEMERGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | disclosed |
| US-4163658-A | 1,2,3-Thiadiazole-5-yl-urea derivatives, process for making the same and plant retardation and defoliation composition containing same | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-08-07 | — | — | US | disclosed |
| US-4130414-A | 1,2,3-Thiadiazole-5-yl-urea derivatives, process for making the same and plant retardation and defoliation composition containing same | SCHERING AG (DE) | 1978-12-19 | — | — | US | disclosed |