Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | LMNA | P02545 | 6/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | BLM | P54132 | 3/20 | 0.63 |
| ▸ | THRB | P10828 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30599557 | 1.00 | MAPT (0.66) | MAPTLMNAMAPK1HSD17B10TRPV1 | |
| SCHEMBL11142996 | 0.89 | MEN1 (0.60) | MAPTLMNAMAPK1HSD17B10TRPV1 | |
| SCHEMBL7565149 | 0.88 | MAPK1 (0.81) | MAPTLMNAMAPK1HSD17B10HPGD | |
| SCHEMBL23727571 | 0.86 | TRPV1 (0.56) | TRPV1MEN1KMT2ABLMTHRB | |
| SCHEMBL11218133 | 0.85 | EPHX2 (0.79) | MAPTLMNAMAPK1MEN1KMT2A | |
| SCHEMBL10944813 | 0.84 | HPGD (0.68) | MAPTLMNAMAPK1TRPV1MEN1 | |
| SCHEMBL11612418 | 0.84 | GPR35 (0.61) | MAPTLMNAMAPK1TRPV1MEN1 | |
| SCHEMBL11266669 | 0.84 | MEN1 (0.63) | MAPTLMNAMAPK1MEN1KMT2A | |
| SCHEMBL27898897 | 0.84 | EPHX2 (0.86) | MAPTLMNAMAPK1MEN1KMT2A | |
| SCHEMBL8885410 | 0.83 | MAPT (0.54) | MAPTLMNAMAPK1HSD17B10TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396473-A | Imidazopyridinyl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-12 | — | — | CN | disclosed |
| CN-115698035-A | Inhibitors of norovirus and coronavirus replication | 共晶制药公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-106008569-A | Boronates as arginase inhibitors, compositions and applications thereof | 马尔斯公司 | 2016-10-12 | — | — | CN | disclosed |
| US-20110155660-A1 | MODIFIED MEMBRANE | DOW GLOBAL TECHNOLOGIES LLC | 2011-06-30 | — | — | US | disclosed |
| US-7882963-B2 | modifying polyamide discriminating layer ( e.g metaphenylene diamine- trimesoyl chloride monomers) with aminoacetophenone or aminothiophenol; fouling resistant surface, improved salt rejection, antimicrobial properties, improved solute, and/or small organics rejection; for water purification | DOW GLOBAL TECHNOLOGIES INC. (US) | 2011-02-08 | — | — | US | disclosed |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| US-20090159527-A1 | MODIFIED MEMBRANE | DOW GLOBAL TECHNOLOGIES LLC | 2009-06-25 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007133362-A1 | MODIFIED MEMBRANE | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-11-22 | — | — | WO | disclosed |
| US-6939887-B2 | Benzimidazolidinone derivatives | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2005-09-06 | — | — | US | disclosed |
| US-20040142850-A1 | Benzimidazolidinone derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2004-07-22 | — | — | US | disclosed |
| EP-1364945-A1 | BENZIMIDAZOLIDINONE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2003-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | MAPT 3312/4885LMNA 3250/4885MAPK1 4726/4885 |
| US-20040142850-A1 | Benzimidazolidinone derivatives | GHSR, GHRHR, PRLHR | MAPT 4756/4885LMNA 3672/4885MAPK1 412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.