Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | PTPRC | P08575 | 5/20 | 0.50 |
| ▸ | S100A4 | P26447 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10947108 | 0.98 | TTR (0.54) | TTRNPC1RAB9AATMPTPRC | |
| SCHEMBL10941912 | 0.98 | TTR (0.54) | TTRNPC1RAB9AATMPTPRC | |
| SCHEMBL10946173 | 0.84 | TTR (0.51) | TTRNPC1RAB9AATMPTPRC | |
| SCHEMBL10942187 | 0.83 | MAOA (0.47) | TTRNPC1RAB9AATMALDH1A1 | |
| SCHEMBL10942389 | 0.83 | SRD5A1 (0.51) | NPC1RAB9AALDH1A1L3MBTL1HPGD | |
| SCHEMBL10947573 | 0.82 | TTR (0.50) | TTRNPC1RAB9AATMPTPRC | |
| SCHEMBL10947811 | 0.82 | NPC1 (0.50) | TTRNPC1RAB9AATMPTPRC | |
| SCHEMBL10941789 | 0.82 | TTR (0.61) | TTRNPC1RAB9AATMPTPRC | |
| SCHEMBL10943587 | 0.81 | TTR (0.59) | TTRNPC1RAB9AATMPTPRC | |
| SCHEMBL10946623 | 0.81 | TTR (0.59) | TTRNPC1RAB9AATMPTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496447-A | PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS AND FOR CURING PRINTING INKS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1985-01-29 | — | — | US | disclosed |
| US-4374984-A | Aromatic-aliphatic ketones useful as photoinitiators | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-02-22 | — | — | US | disclosed |