Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11694568 | 0.87 | APEX1 (0.74) | APEX1KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL10876642 | 0.87 | APEX1 (0.77) | APEX1KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL11593854 | 0.87 | APEX1 (0.81) | APEX1KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL10877295 | 0.86 | APEX1 (0.77) | APEX1KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL1413131 | 0.86 | APEX1 (1.00) | APEX1KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL9411865 | 0.86 | APEX1 (1.00) | APEX1KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL11595946 | 0.86 | APEX1 (0.72) | APEX1KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL5567709 | 0.86 | APEX1 (0.76) | APEX1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL11597022 | 0.85 | APEX1 (0.71) | APEX1KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL11581467 | 0.85 | APEX1 (0.71) | APEX1KMT2AMEN1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4545785-A | FIBER-REACTIVE DYES FOR CELLULOSE | CIBA-GEIGY CORPORATION (US) | 1985-10-08 | — | — | US | disclosed |
| EP-0122881-A1 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1984-10-24 | — | — | EP | disclosed |