Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.76 |
| ▸ | CASP6 | P55212 | 2/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 2/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11440872 | 0.92 | APEX1 (0.63) | APEX1CASP6CTDSP1HDAC1HSD17B10 | |
| SCHEMBL11426178 | 0.92 | APEX1 (0.63) | APEX1CASP6CTDSP1HDAC1HSD17B10 | |
| SCHEMBL11472832 | 0.88 | APEX1 (0.58) | APEX1CASP6CTDSP1HDAC1HSD17B10 | |
| SCHEMBL10876642 | 0.87 | APEX1 (0.77) | APEX1NPSR1ENPP2ALDH1A1KAT6A | |
| SCHEMBL11593854 | 0.87 | APEX1 (0.81) | APEX1CASP6CTDSP1HSD17B10NT5E | |
| SCHEMBL6560534 | 0.86 | APEX1 (0.77) | APEX1CASP6CTDSP1HDAC1NT5E | |
| SCHEMBL11589917 | 0.86 | APEX1 (0.77) | APEX1CASP6CTDSP1HDAC1NT5E | |
| SCHEMBL9411865 | 0.86 | APEX1 (1.00) | APEX1CASP6CTDSP1HDAC1HSD17B10 | |
| SCHEMBL1413131 | 0.86 | APEX1 (1.00) | APEX1CASP6CTDSP1HDAC1HSD17B10 | |
| SCHEMBL10944877 | 0.86 | APEX1 (0.76) | APEX1SMN1; SMN2ENPP2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4103028-A | SUBSTITUTED HYDROXY NAPHTHALENEDISULFONIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1978-07-25 | — | — | US | claimed |
| US-20070151479-A1 | Acidic monoazo dyestuffs | CLARIANT FINANCE (BVI) LIMITED (VG) | 2007-07-05 | — | — | US | disclosed |
| EP-1704187-A1 | ACIDIC MONOAZO DYESTUFFS | CLARIANT INTERNATIONAL LTD. (CH) | 2006-09-27 | — | — | EP | disclosed |
| WO-2005073323-A1 | ACIDIC MONOAZO DYESTUFFS | CLARIANT INTERNATIONAL LTD (CH) | 2005-08-11 | — | — | WO | disclosed |
| EP-1055710-B1 | Water-soluble fibre-reactive dyestuffs, process for their preparation and their use | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 2004-08-11 | — | — | EP | disclosed |
| US-6444794-B1 | COMPLEXING WITH SUBSTRATE | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2002-09-03 | — | — | US | disclosed |
| EP-1055710-A1 | Water-soluble fibre-reactive dyestuffs, process for their preparation and their use | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 2000-11-29 | — | — | EP | disclosed |
| EP-0542079-B1 | Process for continuously reacting halogenopyrimidines with amines | BAYER AG (DE) | 1997-07-23 | — | — | EP | disclosed |
| EP-0548795-B1 | Water-soluble reactive dyes, their manufacture and their use | HOECHST AG (DE) | 1997-07-09 | — | — | EP | disclosed |
| US-5578712-A | Fibre-reactive monoazonaphthyl dyestuffs | SANDOZ LTD. (CH) | 1996-11-26 | — | — | US | disclosed |
| US-5091515-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED 2,4-DIAMINO-6-FLUORO-S-TRIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
| WO-1991009914-A1 | AZO COMPOUNDS, PROCESS FOR PRODUCING THEM AND THEIR USE AS COLORANTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-11 | — | — | WO | disclosed |
| WO-1990013603-A1 | WATER-SOLUBLE AZO DYES, PROCESS FOR PRODUCING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-11-15 | — | — | WO | disclosed |
| US-4929719-A | Fiber-reactive dyes containing an aniline radical which carries two different vinylsulfonyl moieties | CIBA-GEIGY CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |
| US-4875903-A | PRINTING,DYEING | SANDOZ LTD. (CH) | 1989-10-24 | — | — | US | disclosed |
| US-4391824-A | INHIBITING CONNECTIVE TISSUE DISTRUCTION, ENZYME INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1983-07-05 | — | — | US | disclosed |
| EP-0024668-B1 | REACTIVE DYESTUFFS AND THEIR USE IN DYEING AND PRINTING HYDROXYL GROUPS AND NITROGEN CONTAINING MATERIALS | BAYER AG (DE) | 1983-04-13 | — | — | EP | disclosed |
| US-4103028-A | SUBSTITUTED HYDROXY NAPHTHALENEDISULFONIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1978-07-25 | — | — | US | disclosed |
| US-4054559-A | Reactive disazo monohalogenotriazine dyestuffs | NIPPON KAYAKU KABUSHIKI KAISHA (JA) | 1977-10-18 | — | — | US | disclosed |
| US-4046805-A | Substituted-hydroxy-naphthalenedisulfonic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1977-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070151479-A1 | Acidic monoazo dyestuffs | PAH, TYR, CD68 | APEX1 2834/4885CASP6 4675/4885CTDSP1 4084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.