Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11414957 | 0.90 | CYP1A2 (0.62) | CYP1A2CYP2C9CYP2C19CYP3A4DPP4 | |
| SCHEMBL10943177 | 0.86 | CYP1A2 (0.58) | CYP1A2CYP2C9CYP2C19CYP3A4DPP4 | |
| SCHEMBL11819263 | 0.84 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19CYP3A4DPP4 | |
| SCHEMBL8030933 | 0.83 | CYP1A2 (0.62) | CYP1A2CYP2C9CYP2C19CYP3A4SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10423775 | 0.81 | CYP1A2 (0.60) | CYP1A2CYP2C9CYP2C19CYP3A4SMN1; SMN2 | |
| SCHEMBL10937945 | 0.81 | CYP1A2 (0.53) | CYP1A2CYP2C9CYP2C19CYP3A4DPP4 | |
| SCHEMBL22636503 | 0.79 | CYP1A2 (0.54) | CYP1A2CYP2C9CYP2C19CYP3A4DPP4 | |
| SCHEMBL11742164 | 0.79 | CYP1A2 (0.50) | CYP1A2CYP2C9CYP2C19CYP3A4DPP4 | |
| SCHEMBL2398857 | 0.78 | CYP3A4 (0.73) | CYP1A2CYP2C9CYP2C19CYP3A4DPP4 | |
| SCHEMBL307310 | 0.78 | CYP1A2 (1.00) | CYP1A2CYP2C9CYP2C19CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4085141-A | Process for the preparation of anilines meta-substituted by chlorine | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-18 | — | — | US | claimed |
| EP-0069907-B1 | PROCESS FOR PREPARING M-CHLORO-SUBSTITUTED ANILINES | BAYER AG (DE) | 1985-08-28 | — | — | EP | disclosed |
| US-4532350-A | Process for the selective preparation of meta-chloroanilines | RHONE-POULENC AGROCHIMIE (FR) | 1985-07-30 | — | — | US | disclosed |
| US-4495368-A | Process for the preparation of meta-halogenoanilines | RHONE-POULENC AGROCHIMIE (FR) | 1985-01-22 | — | — | US | disclosed |
| EP-0065668-B1 | UREA DERIVATIVES, THEIR PREPARATION AND USE | CELAMERCK GmbH & Co. KG (DE) | 1984-12-12 | — | — | EP | disclosed |
| US-4478852-A | FUNGICIDES | CELAMERCK GMBH & CO. KG. (DE) | 1984-10-23 | — | — | US | disclosed |
| US-4460788-A | Process for preparation of anilines which are m-substituted by chlorine | BAYER AKTIENGESELLSCHAFT (DE) | 1984-07-17 | — | — | US | disclosed |
| EP-0051782-B1 | PROCESS FOR THE MANUFACTURE OF M-HALOGENATED ANILINES | BAYER AG (DE) | 1984-05-23 | — | — | EP | disclosed |
| US-4429156-A | Process for the preparation of m-halogen-substituted anilines | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-31 | — | — | US | disclosed |
| US-4418213-A | HYDRODEHALOGENATION LEWIS ACID AND NOBLE METAL CATALYSTS | RHONE-POULENC AGROCHIMIE (FR) | 1983-11-29 | — | — | US | disclosed |
| EP-0069907-A2 | Process for preparing m-chloro-substituted anilines | BAYER AG (DE) | 1983-01-19 | — | — | EP | disclosed |
| US-4351959-A | Process for preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-09-28 | — | — | US | disclosed |
| US-4340759-A | Process for the preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-07-20 | — | — | US | disclosed |
| EP-0051782-A1 | Process for the manufacture of m-halogenated anilines | BAYER AG (DE) | 1982-05-19 | — | — | EP | disclosed |
| US-4324914-A | Process for preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-04-13 | — | — | US | disclosed |
| US-4193937-A | DECHLORINATION OF CHLOROANILINES, SELECTIVE HYDROGENATION CATALYSTS OF NOBLE METAL AND SULFUR | BAYER AKTIENGESELLSCHAFT (DE) | 1980-03-18 | — | — | US | disclosed |
| US-4085141-A | Process for the preparation of anilines meta-substituted by chlorine | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-18 | — | — | US | disclosed |