SCHEMBL307310

SCHEMBL307310

Nc1cc(Cl)ccc1Oc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 1.00
CYP2C9 P11712 2/20 1.00
CYP2C19 P33261 2/20 1.00
CYP3A4 P08684 2/20 1.00
MAPT P10636 6/20 0.76
SMN1; SMN2 Q16637 5/20 0.76
ALDH1A1 P00352 2/20 0.76
MEN1 O00255 2/20 0.76
KMT2A Q03164 2/20 0.76
KDM4E B2RXH2 2/20 0.76
CYP2D6 P10635 1/20 0.76
HPGD P15428 1/20 0.76
HTT P42858 3/20 0.70
LMNA P02545 3/20 0.70
L3MBTL1 Q9Y468 1/20 0.68
NPSR1 Q6W5P4 1/20 0.48
TDP1 Q9NUW8 2/20 0.45
ALOX15 P16050 2/20 0.45
TSHR P16473 2/20 0.45
TTR P02766 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32674568 0.88 MAPT (0.96) CYP1A2CYP2C9CYP2C19CYP3A4MAPT
SCHEMBL7140487 0.88 MAPT (0.96) CYP1A2CYP2C9CYP2C19CYP3A4MAPT
Hydrochloric Acid SCHEMBL11515445 0.86 MAPT (1.00) CYP1A2CYP2C9CYP2C19CYP3A4MAPT
SCHEMBL2398857 0.85 CYP3A4 (0.73) CYP1A2CYP2C9CYP2C19CYP3A4MAPT
SCHEMBL5863619 0.83 MAPT (0.73) CYP1A2CYP2C9CYP2C19CYP3A4MAPT
SCHEMBL7013006 0.83 CYP1A2 (0.69) CYP1A2CYP2C9CYP2C19CYP3A4MAPT
Acetoacetic Acid SCHEMBL11806407 0.83 CYP1A2 (0.68) CYP1A2CYP2C9CYP2C19CYP3A4MAPT
SCHEMBL3790316 0.82 CYP1A2 (0.69) CYP1A2CYP2C9CYP2C19CYP3A4MAPT
SCHEMBL359771 0.81 SMN1; SMN2 (0.77) CYP1A2CYP2C9CYP2C19CYP3A4MAPT
SCHEMBL11409091 0.81 MAPT (0.77) CYP1A2CYP2C9CYP2C19CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108997134-B Synthesis method of 5-chloro-2-phenoxyaniline and Beta molecular sieve used by same 金华双宏化工有限公司 2021-05-14 CN claimed
CN-110003219-A Pyrazolo [1,5A] pyrimidine and thieno [3,2B] pyrimidine derivatives as IRAK4 regulator 弗·哈夫曼-拉罗切有限公司 2019-07-12 CN claimed
CN-106187787-B A kind of preparation method of 2- amino -4- chlorodiphenyl ether 浙江闰土研究院有限公司 2019-01-22 CN claimed
EP-2593457-B1 PYRAZOLO[1,5A]PYRIMIDINE AND THIENO[3,2B]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS HOFFMANN LA ROCHE (CH) 2017-08-23 EP claimed
CN-106187787-A A kind of preparation method of 2 amino 4 chlorodiphenyl ethers 浙江闰土研究院有限公司 2016-12-07 CN claimed
CN-1245552-C Dyed and/or printed nonwoven fabric CARL FREUDENBERY KG (DE) 2006-03-15 CN claimed
EP-1412578-B1 DYED AND/OR PRINTED NON-WOVEN FABRIC FREUDENBERG CARL KG (DE) 2006-01-04 EP claimed
US-20040194234-A1 Dyed and/or printed non-woven fabric CARL FREUDENBERG KG (DE) 2004-10-07 US claimed
CN-1535342-A Dyed and/or printed non-woven fabric �������ǰظ����Ϲ�˾ 2004-10-06 CN claimed
EP-1412578-A1 DYED AND/OR PRINTED NON-WOVEN FABRIC Carl Freudenberg KG (DE) 2004-04-28 EP claimed
WO-2003014464-A1 DYED AND/OR PRINTED NON-WOVEN FABRIC CARL FREUDENBERG KG (DE) 2003-02-20 WO claimed
US-5244899-A Azabicycloalkyl and azatricycloalkyl amides used to treat inflammation, allergy, asthma and skin disorders G. D. SEARLE AND CO. (US) 1993-09-14 US claimed
US-5198435-A Antiinflammatory, antiallergen G. D. SEARLE & CO. (US) 1993-03-30 US claimed
US-20250129258-A1 AQUEOUS INK, INK CARTRIDGE AND INK JET RECORDING METHOD CANON KK (JP) 2025-04-24 US disclosed
US-12215240-B2 Aqueous ink, ink cartridge and ink jet recording method CANON KABUSHIKI KAISHA (JP) 2025-02-04 US disclosed
CN-118388379-A Organic total synthesis method of nimesulide derivative 大连理工大学 2024-07-26 CN disclosed
US-3998803-A TEXTILES FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) 1976-12-21 US disclosed
US-3971741-A DISPERSION PIGMENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US disclosed
US-3951950-A ANTIVIRAL, CARDIOVASCULAR, ANTIINFLAMMATORY E. R. SQUIBB & SONS, INC. (US) 1976-04-20 US disclosed
US-3951950-A ANTIVIRAL, CARDIOVASCULAR, ANTIINFLAMMATORY E. R. SQUIBB & SONS, INC. (US) 1976-04-20 US disclosed