SCHEMBL10945083

SCHEMBL10945083

ClC=CCc1ccccn1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
MAPT P10636 1/20 0.44
LIN28A Q9H9Z2 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
HRH3 Q9Y5N1 3/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
LMNA P02545 2/20 0.41
HRH4 Q9H3N8 2/20 0.41
TAAR1 Q96RJ0 1/20 0.40
ALDH1A1 P00352 1/20 0.40
ALOX15 P16050 1/20 0.40
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17607340 1.00 HRH1 (0.45) HRH1SMN1; SMN2MAPTLIN28ATDP1
SCHEMBL5645784 0.83
SCHEMBL28985167 0.79 HRH1 (0.50) HRH1SMN1; SMN2MAPTLIN28ATDP1
SCHEMBL10810253 0.79 HRH1 (0.50) HRH1SMN1; SMN2MAPTLIN28ATDP1
SCHEMBL28985180 0.79 HRH1 (0.50) HRH1SMN1; SMN2MAPTLIN28ATDP1
SCHEMBL6159415 0.79 HRH1 (0.45) HRH1SMN1; SMN2MAPTLIN28ATDP1
SCHEMBL1525817 0.79 HRH1 (0.45) HRH1SMN1; SMN2MAPTLIN28ATDP1
SCHEMBL253433 0.79 HRH1 (0.45) HRH1SMN1; SMN2MAPTLIN28ATDP1
SCHEMBL11034424 0.79 HRH1 (0.45) HRH1SMN1; SMN2MAPTLIN28ATDP1
SCHEMBL16992895 0.79 HRH1 (0.45) HRH1SMN1; SMN2MAPTLIN28ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112680730-A Stainless steel product mark etching method 上海易慧机电科技有限公司 2021-04-20 CN claimed
EP-0069033-B1 HERBICIDAL AMIDE AND ESTER DERIVATIVES OF PYRIDINE, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION RHONE-POULENC AGROCHIMIE (FR) 1985-09-04 EP claimed
EP-0112262-A1 Benzylcarbamoylpyridine derivatives RHONE-POULENC AGROCHIMIE (FR) 1984-06-27 EP claimed
EP-0069033-A1 Herbicidal amide and ester derivatives of pyridine, process for their preparation and their application RHONE-POULENC AGROCHIMIE (FR) 1983-01-05 EP claimed
CN-112680730-A Stainless steel product mark etching method 上海易慧机电科技有限公司 2021-04-20 CN disclosed
CN-106957228-B Tung oil-based polyol and preparation method thereof 中国石油化工股份有限公司 2020-08-11 CN disclosed
WO-2016042280-A1 CONJUGATES OF AMINO ACID-PYRIDINE/PYRIDINIUM AND USES THEREOF AS BIOCIDAL AGENTS Université de Nice Sophia Antipolis (FR) 2016-03-24 WO disclosed
US-4566899-A Selective herbicidal benzylcarbamoylpyridine derivatives RHONE-POULENC AGROCHIMIE (FR) 1986-01-28 US disclosed
US-4556414-A Herbicidal dihydropyridine amides RHONE-POULENC AGROCHIMIE (FR) 1985-12-03 US disclosed
EP-0112262-A1 Benzylcarbamoylpyridine derivatives RHONE-POULENC AGROCHIMIE (FR) 1984-06-27 EP disclosed