SCHEMBL253433

SCHEMBL253433

SC=CCc1ccccn1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
MAPT P10636 1/20 0.44
LIN28A Q9H9Z2 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HRH3 Q9Y5N1 1/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
LMNA P02545 2/20 0.41
ALDH1A1 P00352 2/20 0.40
TAAR1 Q96RJ0 1/20 0.40
ALOX15 P16050 1/20 0.40
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
GRIN3A Q8TCU5 1/20 0.39
CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27554216 0.83
SCHEMBL16992895 0.79 HRH1 (0.45) HRH1SMN1; SMN2MAPTLIN28ATDP1
SCHEMBL28985180 0.79 HRH1 (0.50) HRH1SMN1; SMN2MAPTLIN28ATDP1
SCHEMBL28985167 0.79 HRH1 (0.50) HRH1SMN1; SMN2MAPTLIN28ATDP1
SCHEMBL1525817 0.79 HRH1 (0.45) HRH1SMN1; SMN2MAPTLIN28ATDP1
SCHEMBL11034424 0.79 HRH1 (0.45) HRH1SMN1; SMN2MAPTLIN28ATDP1
SCHEMBL6428024 0.79 HRH1 (0.50) HRH1SMN1; SMN2MAPTLIN28ATDP1
SCHEMBL6159415 0.79 HRH1 (0.45) HRH1SMN1; SMN2MAPTLIN28ATDP1
SCHEMBL10810253 0.79 HRH1 (0.50) HRH1SMN1; SMN2MAPTLIN28ATDP1
SCHEMBL248607 0.79 HRH1 (0.50) HRH1SMN1; SMN2MAPTLIN28ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240109831-A1 PROCESS FOR PREPARING BISPHENOL A (BPA) IN THE PRESENCE OF BENZENE COVESTRO DEUTSCHLAND AG (DE) 2024-04-04 US claimed
US-20240076256-A1 PROCESS FOR PREPARING BISPHENOL A (BPA) IN THE PRESENCE OF ALPHA-METHYLSTYRENE COVESTRO DEUTSCHLAND AG (DE) 2024-03-07 US claimed
US-20240001352-A1 CATALYST SYSTEM AND PROCESS FOR PRODUCING BISPHENOL-A BADGER LICENSING LLC 2024-01-04 US claimed
EP-4298083-A1 PROCESS FOR PREPARING BISPHENOL A (BPA) IN THE PRESENCE OF ACETOPHENONE Covestro Deutschland AG (DE) 2024-01-03 EP claimed
EP-4298079-A1 PROCESS FOR PREPARING BISPHENOL A (BPA) IN THE PRESENCE OF BENZENE Covestro Deutschland AG (DE) 2024-01-03 EP claimed
EP-4298084-A1 PROCESS FOR PREPARING BISPHENOL A (BPA) IN THE PRESENCE OF CUMENE Covestro Deutschland AG (DE) 2024-01-03 EP claimed
EP-4298080-A1 PROCESS FOR PREPARING BISPHENOL A (BPA) IN THE PRESENCE OF ALPHA-METHYLSTYRENE Covestro Deutschland AG (DE) 2024-01-03 EP claimed
EP-3847150-B1 PROCESS FOR PRODUCING BISPHENOL-A BADGER LICENSING LLC (US) 2023-11-22 EP claimed
CN-116917261-A Process for the preparation of bisphenol A (BPA) in the presence of benzene 科思创德国股份有限公司 2023-10-20 CN claimed
CN-116897145-A Process for the preparation of bisphenol A (BPA) in the presence of alpha-methylstyrene 科思创德国股份有限公司 2023-10-17 CN claimed
EP-2497574-A1 CATALYST FOR PRODUCTION OF BISPHENOL COMPOUND AND METHOD FOR PRODUCING BISPHENOL COMPOUND Mitsubishi Chemical Corporation (JP) 2012-09-12 EP claimed
US-7129382-B2 Process for producing bisphenol A IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2006-10-31 US claimed
EP-1686116-A1 PROCESS FOR PRODUCTION OF PYRIDYLETHYLTHIO COMPOUNDS, MODIFIED ION EXCHANGERS, PROCESS FOR PRODUCTION THEREOF, AND PROCESS FOR PRODUCTION OF BISPHENOLS Mitsubishi Chemical Corporation (JP) 2006-08-02 EP claimed
US-20060041145-A1 Process for producing pyridylethylthio compound, modified ion exchanger and process for producing the same, and process for producing bisphenol compound MITSUBISHI CHEMICAL CORPORATION (JP) 2006-02-23 US claimed
US-6946581-B2 Bisphenol compound composition having excellent thermal stability MITSUBISHI CHEMICAL CORPORATION (JP) 2005-09-20 US claimed
US-20040192975-A1 Process for producing bisphenol A IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-09-30 US claimed
US-6740784-B2 CONDENSATION REACTION BETWEEN PHENOL AND ACETONE USING AN ACID TYPE ION EXCHANGE RESIN MODIFIED IN PART WITH A SULFUR-CONTAINING AMINE COMPOUND; SUPPRESSED DETERIORATION OF CATALYST DUE TO METHANOL IMPURITY IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-05-25 US claimed
US-20030234381-A1 Bisphenol compound composition having excellent thermal stability MITSUBISHI CHEMICAL CORPORATION (JP) 2003-12-25 US claimed
EP-1371623-A1 PROCESS FOR PRODUCING BISPHENOL A IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-12-17 EP claimed
US-20030153792-A1 Process for producing bisphenol a IDEMITSU KOSAN CO. LTD. (JP) 2003-08-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060041145-A1 Process for producing pyridylethylthio compound, modified ion exchanger and process for producing the same, and process for producing bisphenol compound PAH, SLC19A2, PLPBP HRH1 198/4885SMN1; SMN2 4272/4885MAPT 2084/4885
US-20240001352-A1 CATALYST SYSTEM AND PROCESS FOR PRODUCING BISPHENOL-A ARSA, CREBBP, PSPH HRH1 3273/4885SMN1; SMN2 4806/4885MAPT 3908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.