Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL786021 | 0.90 | HMGCR (0.42) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL15844297 | 0.90 | HMGCR (0.42) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL9351424 | 0.90 | HMGCR (0.42) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL11863591 | 0.84 | HMGCR (0.38) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL11863587 | 0.84 | HMGCR (0.38) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL19280362 | 0.73 | HMGCR (0.48) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL901520 | 0.71 | — | — | |
| SCHEMBL13703709 | 0.71 | ACHE (0.31) | — | |
| SCHEMBL27673 | 0.69 | NAALAD2 (0.38) | HMGCRCHRM1TBXA2RADRA1AHIF1A | |
| SCHEMBL27672 | 0.69 | NAALAD2 (0.38) | HMGCRCHRM1TBXA2RADRA1AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8344090-B2 | PDMS-PVP block copolymers | DSM IP ASSETS B.V. (NL) | 2013-01-01 | — | — | US | disclosed |
| US-8153728-B2 | PDMS-PVP block copolymers | DSM IP ASSETS B.V. (NL) | 2012-04-10 | — | — | US | disclosed |
| US-20120083573-A1 | NOVEL PDMS-PVP BLOCK COPOLYMERS | PARAKKA JAMES (US) | 2012-04-05 | — | — | US | disclosed |
| US-20100099829-A1 | NOVEL PDMS-PVP BLOCK COPOLYMERS | THE POLYMER TECHNOLOGY GROUP INCORPORATED (US) | 2010-04-22 | — | — | US | disclosed |